# Bromodomain containing 4

> mammalian protein found in Mus musculus

**Wikidata**: [Q21496156](https://www.wikidata.org/wiki/Q21496156)  
**Source**: https://4ort.xyz/entity/bromodomain-containing-4-q21496156


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9ESU6)
3. Q20641742
4. [The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
6. [The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
7. [Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
8. [Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
9. [BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ESU6&geneProductId=UniProtKB:Q9ESU6)
10. [BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
11. [Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
12. [A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
13. [Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ESU6&geneProductId=UniProtKB:Q9ESU6)
15. [Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ESU6)
16. ensembl Release 106