# BRCA1 associated RING domain 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21100416](https://www.wikidata.org/wiki/Q21100416)  
**Source**: https://4ort.xyz/entity/brca1-associated-ring-domain-1-q21100416


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
4. [BARD1 regulates BRCA1 apoptotic function by a mechanism involving nuclear retention](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
5. [BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
6. [BRCA1 supports XIST RNA concentration on the inactive X chromosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
7. [BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
8. [The UBXN1 Protein Associates with Autoubiquitinated Forms of the BRCA1 Tumor Suppressor and Inhibits Its Enzymatic Function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
9. [The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
10. [Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
11. [Identification of a RING protein that can interact in vivo with the BRCA1 gene product](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
12. [Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
13. [Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
14. [BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
15. [PALB2 is an integral component of the BRCA complex required for homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
16. [DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
17. [A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
18. [E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
19. [Nuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
20. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
21. [Function of BRCA1 in the DNA Damage Response Is Mediated by ADP-Ribosylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
22. [Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
23. [NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
24. [MERIT40 facilitates BRCA1 localization and DNA damage repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
25. [Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
26. [BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
27. [Nuclear targeting and cell cycle regulatory function of human BARD1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728)
28. Ensembl Release 99