# Brain-derived neurotrophic factor

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28562650](https://www.wikidata.org/wiki/Q28562650)  
**Source**: https://4ort.xyz/entity/brain-derived-neurotrophic-factor-q28562650


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P23363)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
5. [Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
6. [Increased expression of brain-derived neurotrophic factor induces formation of basal dendrites and axonal branching in dentate granule cells in hippocampal explant cultures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
8. [Lumbar transplant of neurons genetically modified to secrete brain-derived neurotrophic factor attenuates allodynia and hyperalgesia after sciatic nerve constriction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
9. [Single-cell characterization of retrograde signaling by brain-derived neurotrophic factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
10. [Patterns of expression of brain-derived neurotrophic factor and tyrosine kinase B mRNAs and distribution and ultrastructural localization of their proteins in the visual pathway of the adult rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
11. [Brain-derived neurotrophic factor is an anterograde survival factor in the rat visual system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
12. [Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
13. [BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
14. [Tooth pulp inflammation increases brain-derived neurotrophic factor expression in rodent trigeminal ganglion neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
15. [BDNF increases rat brain mitochondrial respiratory coupling at complex I, but not complex II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
16. [Impact of Changes in Neurotrophic Supplementation on Development of Alzheimer's Disease-Like Pathology in Oxys Rats.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
17. [Brain-derived neurotrophic factor promotes adaptive plasticity within the spinal cord and mediates the beneficial effects of controllable stimulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
18. [Temporal and spatial differences in expression of TrkB isoforms in rat retina during constant light exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
19. [Brain-Derived Neurotrophic Factor as a Biomarker in Primary Open-Angle Glaucoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
20. [Administration of thyroid hormone increases reelin and brain-derived neurotrophic factor expression in rat hippocampus in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
21. [BDNF is expressed in skeletal muscle satellite cells and inhibits myogenic differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
22. [Impact of sound exposure and aging on brain-derived neurotrophic factor and tyrosine kinase B receptors levels in dorsal cochlear nucleus 80 days following sound exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
23. [Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
24. [Up-regulation of the neuronal serotoninergic phenotype in vitro: BDNF and cAMP share Trk B-dependent mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
25. [The anterogradely transported BDNF promotes retinal axon remodeling during eye specific segregation within the LGN](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
26. [Substrate-mediated nanoparticle/gene delivery to MSC spheroids and their applications in peripheral nerve regeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
27. [Prefrontal cortex, caloric restriction and stress during aging: studies on dopamine and acetylcholine release, BDNF and working memory](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
28. [A saturated-fat diet aggravates the outcome of traumatic brain injury on hippocampal plasticity and cognitive function by reducing brain-derived neurotrophic factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
29. [Brain-derived neurotrophic factor signaling rewrites the glucocorticoid transcriptome via glucocorticoid receptor phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
30. [Total and mitochondrial nitrosative stress, decreased brain-derived neurotrophic factor (BDNF) levels and glutamate uptake, and evidence of endoplasmic reticulum stress in the hippocampus of vitamin A-treated rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
31. [Axonal protection by brain-derived neurotrophic factor associated with CREB phosphorylation in tumor necrosis factor-alpha-induced optic nerve degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
32. [Activity-dependent release of endogenous brain-derived neurotrophic factor from primary sensory neurons detected by ELISA in situ](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
33. [BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
34. [Phencyclidine (PCP)-induced disruption in cognitive performance is gender-specific and associated with a reduction in brain-derived neurotrophic factor (BDNF) in specific regions of the female rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
35. [Hyperoxia enhances brain-derived neurotrophic factor and tyrosine kinase B receptor expression in peribronchial smooth muscle of neonatal rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
36. [Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
37. [Müller Cells as a source of brain-derived neurotrophic factor in the retina: noradrenaline upregulates brain-derived neurotrophic factor levels in cultured rat Müller cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
38. [General anesthesia activates BDNF-dependent neuroapoptosis in the developing rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
39. [Brain-derived neurotrophic factor regulates surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid receptors by enhancing the N-ethylmaleimide-sensitive factor/GluR2 interaction in developing neocortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
40. [Glutamate stimulates neurotrophin expression in cultured Müller cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
41. [Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
42. [Extension of optic nerve fibers on genetically modified cells producing brain-derived neurotrophic factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23363)
43. ensembl Release 106