# BR serine/threonine kinase 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110488](https://www.wikidata.org/wiki/Q21110488)  
**Source**: https://4ort.xyz/entity/br-serine-threonine-kinase-2


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8IWQ3)
4. [Swiss-Prot](http://www.uniprot.org/uniprot/Q8IWQ3.txt?version=138)
5. Q20641742
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
7. [BRSK2 is a valosin-containing protein (VCP)-interacting protein that affects VCP functioning in endoplasmic reticulum-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
8. [LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWQ3&geneProductId=UniProtKB:Q8IWQ3)
10. [Phosphorylation of microtubule‐associated protein tau by AMPK‐related kinases](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWQ3&geneProductId=UniProtKB:Q8IWQ3)
11. [LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWQ3&geneProductId=UniProtKB:Q8IWQ3)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
13. [Roles of tau protein in health and disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
14. [Phosphorylation of microtubule‐associated protein tau by AMPK‐related kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
15. [APC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWQ3&geneProductId=UniProtKB:Q8IWQ3)
16. [BRSK2 is regulated by ER stress in protein level and involved in ER stress-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWQ3&geneProductId=UniProtKB:Q8IWQ3)
17. [BRSK2 is a valosin-containing protein (VCP)-interacting protein that affects VCP functioning in endoplasmic reticulum-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWQ3&geneProductId=UniProtKB:Q8IWQ3)
18. [BRSK2 is regulated by ER stress in protein level and involved in ER stress-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
19. [APC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
20. [Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
21. [Microtubule stabilization specifies initial neuronal polarization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWQ3)
22. Ensembl Release 99