# Bone morphogenetic protein 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q14903156](https://www.wikidata.org/wiki/Q14903156)  
**Source**: https://4ort.xyz/entity/bone-morphogenetic-protein-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P21274)
3. Q20641742
4. [Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21274&geneProductId=UniProtKB:P21274)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21274&geneProductId=UniProtKB:P21274)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
8. [Effect of rhBMP-2 on the osteogenic potential of bone marrow stromal cells from an osteogenesis imperfecta mouse (oim)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
9. [A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
10. [WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
11. [PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
12. [Microfibril-associated Glycoprotein 2 (MAGP2) Loss of Function Has Pleiotropic Effects in Vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
13. [Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
14. [A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
15. [The NH2-terminal propeptide of type I procollagen acts intracellularly to modulate cell function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
16. [BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
17. [Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
18. [RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
19. [Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
20. [Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21274&geneProductId=UniProtKB:P21274)
21. [Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
22. [Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
23. [Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
24. [Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
25. [Patterning of the Dorsal Telencephalon and Cerebral Cortex by a Roof Plate-Lhx2 Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
26. [Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
27. [Indian and sonic hedgehogs regulate synchondrosis growth plate and cranial base development and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
28. [Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
29. [Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
30. [Glypican-3 modulates inhibitory Bmp2-Smad signaling to control renal development in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
31. [Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
32. [Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
33. [Antagonistic Interactions between FGF and BMP Signaling Pathways: A Mechanism for Positioning the Sites of Tooth Formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
34. [Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
35. [Novel regulators of bone formation: molecular clones and activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
36. [Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
37. [Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
38. [Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
39. [Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
40. [Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
41. [TIEG1 null mouse-derived osteoblasts are defective in mineralization and in support of osteoclast differentiation in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
42. [Id4 is required for the correct timing of neural differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
43. [Astrocyte differentiation mediated by LIF in cooperation with BMP2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
44. [Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
45. [Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
46. [A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21274)
47. [Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21274&geneProductId=UniProtKB:P21274)
48. [Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21274&geneProductId=UniProtKB:P21274)
49. [Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21274&geneProductId=UniProtKB:P21274)
50. [Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21274&geneProductId=UniProtKB:P21274)