# Beta-site APP cleaving enzyme 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14891894](https://www.wikidata.org/wiki/Q14891894)  
**Source**: https://4ort.xyz/entity/beta-site-app-cleaving-enzyme-1-q14891894


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P56818)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
5. [Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
7. [Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
8. [An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
9. [Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP](http://www.ebi.ac.uk/QuickGO/annotations?protein=P56818&geneProductId=UniProtKB:P56818)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P56818&geneProductId=UniProtKB:P56818)
11. [Spatial segregation of gamma-secretase and substrates in distinct membrane domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=P56818&geneProductId=UniProtKB:P56818)
12. [Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
13. [Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P56818&geneProductId=UniProtKB:P56818)
14. [Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
15. [Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
16. [Spatial segregation of gamma-secretase and substrates in distinct membrane domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
17. [Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
18. [BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
19. [The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
20. [Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
21. [Mossy fiber long-term potentiation deficits in BACE1 knock-outs can be rescued by activation of alpha7 nicotinic acetylcholine receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56818)
22. ensembl Release 106