# Beta-2-microglobulin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q287896](https://www.wikidata.org/wiki/Q287896)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Beta-2_microglobulin)  
**Source**: https://4ort.xyz/entity/beta-2-microglobulin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P61769)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
6. [The crystal structure of human CD1b with a bound bacterial glycolipid](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
7. [Molecular mechanism of lipopeptide presentation by CD1a](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
8. [The association of MHC class I proteins with the 2B4 receptor inhibits self-killing of human NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
9. [MR1 presents microbial vitamin B metabolites to MAIT cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
10. [TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
11. [Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
12. [Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
13. [N-glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
14. [The Q283P amino-acid change in HFE leads to structural and functional consequences similar to those described for the mutated 282Y HFE protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
15. [Novel Interaction between Proliferating Cell Nuclear Antigen and HLA I on the Surface of Tumor Cells Inhibits NK Cell Function through NKp44](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
16. [The binding of TAPBPR and Tapasin to MHC class I is mutually exclusive](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
17. [Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
18. [Crystal Structure of the Hemochromatosis Protein HFE and Characterization of Its Interaction with Transferrin Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
19. [The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
20. [The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
21. [D-strand perturbation and amyloid propensity in beta-2 microglobulin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
22. [Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic  2-microglobulin variant](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
23. [3D structure of amyloid protofilaments of beta2-microglobulin fragment probed by solid-state NMR.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
24. [A recurrent D-strand association interface is observed in β-2 microglobulin oligomers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
25. [Ultrasonication-dependent production and breakdown lead to minimum-sized amyloid fibrils.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
26. [A regulatable switch mediates self-association in an immunoglobulin fold](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
27. [β2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
28. [Protein-induced photophysical changes to the amyloid indicator dye thioflavin T](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
29. [Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
30. [Fibrillogenic propensity of the GroEL apical domain: a Janus-faced minichaperone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
31. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
32. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
33. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
34. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
35. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
36. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
37. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
38. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
39. [Human colostrum: identification of minor proteins in the aqueous phase by proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
40. [Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)
41. [Human colostrum: identification of minor proteins in the aqueous phase by proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
42. [Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
43. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
44. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
45. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
46. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
47. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
48. [Distinct functions for the glycans of tapasin and heavy chains in the assembly of MHC class I molecules.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
49. [HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61769)
50. [Novel Antibacterial Activity of β2-Microglobulin in Human Amniotic Fluid](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61769&geneProductId=UniProtKB:P61769)