# Beclin 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28557341](https://www.wikidata.org/wiki/Q28557341)  
**Source**: https://4ort.xyz/entity/beclin-1


## References

1. UniProt
2. Q20641742
3. [Nupr1/Chop signal axis is involved in mitochondrion-related endothelial cell apoptosis induced by methamphetamine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
4. [Ambra1 modulates starvation-induced autophagy through AMPK signaling pathway in cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
6. [BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
8. [Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
9. [Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
10. [Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
11. [Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
12. [Excessive autophagy contributes to neuron death in cerebral ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
13. [Beclin 1 knockdown retards re-endothelialization and exacerbates neointimal formation via a crosstalk between autophagy and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
14. [Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
15. [Change of autophagy in endplate chondrocytes of rats during aging process](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
16. [Induction of Autophagic Cell Death in the Rat Brain Caused by Iron](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
17. [Effect of chronic lead exposure on expression of autophagy-associated proteins in rat hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
18. [Involvement of autophagy in hypoxic-excitotoxic neuronal death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
19. [Autophagy in the heart and liver during normal aging and calorie restriction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
20. [Autophagy is upregulated in rats with status epilepticus and partly inhibited by Vitamin E](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
21. [Increased Macroautophagy in the Pathological Process of Intervertebral Disc Degeneration in Rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
22. [Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
23. [Autophagy and apoptosis in tubular cells following unilateral ureteral obstruction are associated with mitochondrial oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
24. [Aluminum maltolate induces primary rat astrocyte apoptosis via overactivation of the class III PI3K/Beclin 1-dependent autophagy signal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
25. [Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and JNK activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
26. [Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
27. [Regulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XJ1)
28. ensembl Release 106