# BCL2 like 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109504](https://www.wikidata.org/wiki/Q21109504)  
**Source**: https://4ort.xyz/entity/bcl2-like-2


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL443684)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q92843)
4. Q20641742
5. [Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
6. [Crystal structure of a BCL-W domain-swapped dimer: implications for the function of BCL-2 family proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
7. [Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
8. [Molecular basis of the interaction between the antiapoptotic Bcl-2 family proteins and the proapoptotic protein ASPP2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
9. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
10. [Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
11. [Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
12. [Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
13. [Human Bop is a novel BH3-only member of the Bcl-2 protein family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
14. [Pooled-matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
15. [The structure and interactions of the proline-rich domain of ASPP2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
17. [Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92843&geneProductId=UniProtKB:Q92843)
20. [bcl-w, a novel member of the bcl-2 family, promotes cell survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
21. [Testicular degeneration in Bclw-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92843&geneProductId=UniProtKB:Q92843)
22. [Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92843&geneProductId=UniProtKB:Q92843)
23. [Testicular degeneration in Bclw-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92843)
24. Ensembl Release 99
25. Transporter Classification database