# BCL2 binding component 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q21497067](https://www.wikidata.org/wiki/Q21497067)  
**Source**: https://4ort.xyz/entity/bcl2-binding-component-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q99ML1)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
5. [Structural plasticity underpins promiscuous binding of the prosurvival protein A1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
6. [PUMA couples the nuclear and cytoplasmic proapoptotic function of p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
7. [PUMA induces the rapid apoptosis of colorectal cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
8. [PUMA induces the rapid apoptosis of colorectal cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99ML1&geneProductId=UniProtKB:Q99ML1)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99ML1&geneProductId=UniProtKB:Q99ML1)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
11. [Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99ML1&geneProductId=UniProtKB:Q99ML1)
12. [CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99ML1&geneProductId=UniProtKB:Q99ML1)
13. [Puma is required for p53-induced depletion of adult stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
14. [CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
15. [Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
16. [CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
17. [The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99ML1&geneProductId=UniProtKB:Q99ML1)
18. [p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99ML1&geneProductId=UniProtKB:Q99ML1)
19. [Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
20. [Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
21. [Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99ML1&geneProductId=UniProtKB:Q99ML1)
22. [Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99ML1&geneProductId=UniProtKB:Q99ML1)
23. [p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
24. [The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
25. [Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
26. [Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99ML1)
27. ensembl Release 106