# BCL2-associated agonist of cell death

> mammalian protein found in Mus musculus

**Wikidata**: [Q14907709](https://www.wikidata.org/wiki/Q14907709)  
**Source**: https://4ort.xyz/entity/bcl2-associated-agonist-of-cell-death-q14907709


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q61337)
3. Q20641742
4. [Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
5. [Phosphorylation of Bcl-associated death protein (Bad) by erythropoietin-activated c-Jun N-terminal protein kinase 1 contributes to survival of erythropoietin-dependent cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
6. [Dual role of proapoptotic BAD in insulin secretion and beta cell survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
7. [BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
8. [GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
9. [The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
10. [Type IX collagen knock-out mouse shows progressive hearing loss](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
11. [Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
12. [BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
13. [Inactivation of BAD by IKK Inhibits TNFα-Induced Apoptosis Independently of NF-κB Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
14. [Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
15. [Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
16. [14-3-3 Inhibits Bad-Induced Cell Death through Interaction with Serine-136](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
17. [Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
18. [Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
19. [Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
20. [Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
21. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
22. [GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
23. [Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
26. [Pro- and anti-apoptotic members of the Bcl-2 family in skeletal muscle: a distinct role for Bcl-2 in later stages of myogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
27. [Cyclooxygenase-2-dependent phosphorylation of the pro-apoptotic protein Bad inhibits tonicity-induced apoptosis in renal medullary cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
28. [Cloning of zebrafish BAD, a BH3-only proapoptotic protein, whose overexpression leads to apoptosis in COS-1 cells and zebrafish embryos](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
29. [Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
30. [Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
31. [BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
32. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
33. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
34. [Cloning of zebrafish BAD, a BH3-only proapoptotic protein, whose overexpression leads to apoptosis in COS-1 cells and zebrafish embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
35. [Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
36. [Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
37. [Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
38. [JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
39. [BAD is a pro-survival factor prior to activation of its pro-apoptotic function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
40. [Identification of a Novel Phosphorylation Site, Ser-170, as a Regulator of Bad Pro-apoptotic Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
41. [Expression of Bcl-2 family during liver regeneration and identification of Bcl-x as a delayed early response gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61337)
42. [Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61337&geneProductId=UniProtKB:Q61337)
43. ensembl Release 106