# Basic helix-loop-helix family member e40

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116233](https://www.wikidata.org/wiki/Q21116233)  
**Source**: https://4ort.xyz/entity/basic-helix-loop-helix-family-member-e40-q21116233


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O14503)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
5. [Functional analysis of the basic helix‐loop‐helix transcription factor DEC1 in circadian regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
6. [The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
7. [Molecular Characterization of the Novel Basic Helix–Loop–Helix Protein DEC1 Expressed in Differentiated Human Embryo Chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
8. [DEC1 modulates the circadian phase of clock gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
9. [DEC1 Negatively Regulates the Expression of DEC2 through Binding to the E-box in the Proximal Promoter](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
10. [DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
11. [Dec1 and Dec2 are regulators of the mammalian molecular clock](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
12. [A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
13. [Stra13 is induced by genotoxic stress and regulates ionizing-radiation-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
14. [Regulation of STRA13 by the von Hippel-Lindau Tumor Suppressor Protein, Hypoxia, and the UBC9/Ubiquitin Proteasome Degradation Pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
15. [Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
16. [Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
17. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
18. [Differentiated embryo-chondrocyte expressed gene 1 regulates p53-dependent cell survival versus cell death through macrophage inhibitory cytokine-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
19. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
20. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14503&geneProductId=UniProtKB:O14503)
22. Ensembl Release 99