# Baculoviral IAP repeat containing 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21111704](https://www.wikidata.org/wiki/Q21111704)  
**Source**: https://4ort.xyz/entity/baculoviral-iap-repeat-containing-2-q21111704


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13490)
3. Q20641742
4. [The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
7. [Asymmetric Recruitment of cIAPs by TRAF2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
8. [cIAP1 Localizes to the nuclear compartment and modulates the cell cycle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
9. [The USP19 Deubiquitinase Regulates the Stability of c-IAP1 and c-IAP2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
10. [Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Can Regulate E2F1 Transcription Factor-mediated Control of Cyclin Transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
11. [Middle domain of human Hsp90 isoforms differentially binds Aha1 in human cells and alters Hsp90 activity in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
12. [TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
13. [Distinct BIR Domains of cIAP1 Mediate Binding to and Ubiquitination of Tumor Necrosis Factor Receptor-associated Factor 2 and Second Mitochondrial Activator of Caspases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
14. [Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
15. [cIAP1/2 Are Direct E3 Ligases Conjugating Diverse Types of Ubiquitin Chains to Receptor Interacting Proteins Kinases 1 to 4 (RIP1–4)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
16. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
17. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
18. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
19. [TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
20. [ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
21. [Network organization of the human autophagy system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
22. [OTUB1 modulates c‐IAP1 stability to regulate signalling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
23. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
24. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
25. [IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
26. [A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
27. [Self-termination of the terminator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
28. [The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
29. [Interaction of heat-shock protein 90β isoform (HSP90β) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
30. [Ubiquitin Protein Ligase Activity of IAPs and Their Degradation in Proteasomes in Response to Apoptotic Stimuli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
31. [Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
32. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13490&geneProductId=UniProtKB:Q13490)
33. [cIAP1 Localizes to the nuclear compartment and modulates the cell cycle](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13490&geneProductId=UniProtKB:Q13490)
34. [Interaction of heat-shock protein 90β isoform (HSP90β) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13490&geneProductId=UniProtKB:Q13490)
35. [The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13490&geneProductId=UniProtKB:Q13490)
36. [cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
37. [To fight or die — inhibitor of apoptosis proteins at the crossroad of innate immunity and death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
38. [Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
39. [IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
40. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13490&geneProductId=UniProtKB:Q13490)
41. [The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
42. [IAPS : More than just inhibitors of apoptosis proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
43. [Large-scale identification and characterization of human genes that activate NF-κB and MAPK signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490)
44. Ensembl Release 99