# B cell leukemia/lymphoma 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q14863583](https://www.wikidata.org/wiki/Q14863583)  
**Source**: https://4ort.xyz/entity/b-cell-leukemia-lymphoma-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P10417)
3. Q20641742
4. [Calcium-dependent interaction of calcineurin with Bcl-2 in neuronal tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
5. [c-Myc is essential for urokinase plasminogen activator expression on hypoxia-induced vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
6. [PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
8. [Dual role of proapoptotic BAD in insulin secretion and beta cell survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
9. [BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
10. [Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
11. [Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
12. [Proapoptotic activity of ITM2B(s), a BH3-only protein induced upon IL-2-deprivation which interacts with Bcl-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
13. [Involvement of heat shock protein (Hsp)90 beta but not Hsp90 alpha in antiapoptotic effect of CpG-B oligodeoxynucleotide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
14. [Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
15. [Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
16. [BID: a novel BH3 domain-only death agonist](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
17. [Endogenous HMGB1 regulates autophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
18. [IAN family critically regulates survival and development of T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
19. [Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
20. [Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
21. [Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
22. [Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
23. [Upregulation of Bcl2 inhibits apoptosis-driven BAX insertion but favors BAX relocalization in mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
24. [Deacetylation of p53 induces autophagy by suppressing Bmf expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
25. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
26. [Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
27. [BID: a novel BH3 domain-only death agonist](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
28. [Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
29. [Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
30. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
31. [Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
32. [Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
33. [Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
34. [Role of BCL-2 in the survival and function of developing and mature sympathetic neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
35. [Bcl-2 protein expression during murine development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
36. [Up-regulation of bax and down-regulation of bc1–2 is associated with kainate-induced apoptosis in mouse brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
37. [Differential regulation of bcl-2, bax, c-fos, junB, and krox-24 expression in the cerebellum of Purkinje cell degeneration mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
38. [Targeted Disruption of the PDZK1 Gene in Mice Causes Tissue-specific Depletion of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I and Altered Lipoprotein Metabolism](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
39. [A novel transactivating factor that regulates interferon-gamma-dependent gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
40. [Bcl-2 protein expression during murine development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
41. [The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
42. [The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
43. [Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
44. [Sorting specificity of spermatogenic cell specific region of mouse hexokinase-s (mHk1-s)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
45. [Expression of Bcl-2 protein in murine neural cells in culture](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
46. [Bcl-2 overexpression abolishes early calcium waving preceding apoptosis in NIH-3T3 murine fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
47. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10417&geneProductId=UniProtKB:P10417)
48. [Bcl-2 overexpression abolishes early calcium waving preceding apoptosis in NIH-3T3 murine fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
49. [Expression of Bcl-2 protein in murine neural cells in culture](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)
50. [Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10417)