# AXL receptor tyrosine kinase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21201523](https://www.wikidata.org/wiki/Q21201523)  
**Source**: https://4ort.xyz/entity/axl-receptor-tyrosine-kinase


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL3301622)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P30530)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
6. [The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
7. [Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
8. [Gas6-mediated signaling is dependent on the engagement of its gamma-carboxyglutamic acid domain with phosphatidylserine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
9. [Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
10. [Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
11. [Structural basis for Gas6-Axl signalling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
12. [AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
13. [axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30530&geneProductId=UniProtKB:P30530)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30530&geneProductId=UniProtKB:P30530)
15. [Axl is essential for VEGF-A-dependent activation of PI3K/Akt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
16. [axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
18. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30530&geneProductId=UniProtKB:P30530)
19. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30530&geneProductId=UniProtKB:P30530)
20. [Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
21. [Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30530&geneProductId=UniProtKB:P30530)
22. [Quantitative proteomics identifies a Dab2/integrin module regulating cell migration](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30530&geneProductId=UniProtKB:P30530)
23. [Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
24. [Quantitative proteomics identifies a Dab2/integrin module regulating cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
25. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
26. [The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
27. [The Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30530)
28. [The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30530&geneProductId=UniProtKB:P30530)
29. Ensembl Release 99
30. UMLS 2023