# Axin Dmel_CG7926

> protein found in Drosophila melanogaster

**Wikidata**: [Q29817164](https://www.wikidata.org/wiki/Q29817164)  
**Source**: https://4ort.xyz/entity/axin-dmel-cg7926


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9V407)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V407&geneProductId=UniProtKB:Q9V407)
5. [Wnt pathway activation by ADP-ribosylation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
6. [In vivo analysis in Drosophila reveals differential requirements of contact residues in Axin for interactions with GSK3beta or beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
8. [Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interference](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
9. [Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
10. [Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
11. [The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
12. [Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
13. [A Drosophila Axin homolog, Daxin, inhibits Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
14. [The role of Wingless signaling in establishing the anteroposterior and dorsoventral axes of the eye disc.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
15. [Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
16. [Hyperactivated Wnt Signaling Induces Synthetic Lethal Interaction with Rb Inactivation by Elevating TORC1 Activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
17. [Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
18. [Wingless signaling regulates the maintenance of ovarian somatic stem cells in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
19. [Drosophilahomeodomain-interacting protein kinase inhibits the Skp1-Cul1-F-box E3 ligase complex to dually promote Wingless and Hedgehog signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
20. [Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
21. [The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
22. [RanBP3 enhances nuclear export of active (beta)-catenin independently of CRM1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
23. [Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V407)
24. ensembl Release 106