# Axin 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28562512](https://www.wikidata.org/wiki/Q28562512)  
**Source**: https://4ort.xyz/entity/axin-1-q28562512


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O70239)
3. Q20641742
4. [Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
5. [The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
6. [Synaptic scaffolding molecule interacts with axin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
7. [Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
8. [DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
9. [Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
10. [Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2to LRP6 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
11. [Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
12. [An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
13. [Inhibition of Wnt signaling pathway by a novel axin-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
15. [The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
16. [Cyclin-dependent kinase 2 regulates the interaction of Axin with beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70239)
17. ensembl Release 106