# Autophagy related 12

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116762](https://www.wikidata.org/wiki/Q21116762)  
**Source**: https://4ort.xyz/entity/autophagy-related-12


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O94817)
3. Q20641742
4. [Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
5. [The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
6. [A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
7. [Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
8. [Network organization of the human autophagy system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
9. [Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
10. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
13. [WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94817)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94817&geneProductId=UniProtKB:O94817)
15. Ensembl Release 99
16. UMLS 2023
17. Transporter Classification database