# Automated de novo molecular design by hybrid machine intelligence and rule-driven chemical synthesis

> Research article (Nature Machine Intelligence, 2019) · cited 110× · AI/ML

**Wikidata**: [openalex:W2955727640](https://www.wikidata.org/wiki/openalex:W2955727640)  
**Source**: https://4ort.xyz/entity/automated-de-novo-molecular-design-by-hybrid-machine-intelligence-and-rule-driven-chemical-synthesis