# autocrine motility factor receptor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112658](https://www.wikidata.org/wiki/Q21112658)  
**Source**: https://4ort.xyz/entity/autocrine-motility-factor-receptor-q21112658


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UKV5)
3. Q20641742
4. [USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
5. [A Ubiquitin Ligase-Associated Chaperone Holdase Maintains Polypeptides in Soluble States for Proteasome Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
6. [SGTA Recognizes a Noncanonical Ubiquitin-like Domain in the Bag6-Ubl4A-Trc35 Complex to Promote Endoplasmic Reticulum-Associated Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
7. [USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
8. [A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
11. [Sterol-regulated Degradation of Insig-1 Mediated by the Membrane-bound Ubiquitin Ligase gp78](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
12. [Gp78, a Membrane-Anchored Ubiquitin Ligase, Associates with Insig-1 and Couples Sterol-Regulated Ubiquitination to Degradation of HMG CoA Reductase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
13. [Ufd1 Is a Cofactor of gp78 and Plays a Key Role in Cholesterol Metabolism by Regulating the Stability of HMG-CoA Reductase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
14. [CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
15. [The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
16. [Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
17. [RING finger palmitoylation of the endoplasmic reticulum Gp78 E3 ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
18. [Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
19. [The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
20. [Identification of VCP/p97, Carboxyl Terminus of Hsp70-interacting Protein (CHIP), and Amphiphysin II Interaction Partners Using Membrane-based Human Proteome Arrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
21. [Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
22. [Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
23. [Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
24. [Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
25. [A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
26. [Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
28. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
29. [Identification of SVIP as an Endogenous Inhibitor of Endoplasmic Reticulum-associated Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
30. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
31. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
32. [Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
33. [ER stress differentially regulates the stabilities of ERAD ubiquitin ligases and their substrates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
34. [Function of the p97–Ufd1–Npl4 complex in retrotranslocation from the ER to the cytosol](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKV5)
35. [Function of the p97–Ufd1–Npl4 complex in retrotranslocation from the ER to the cytosol](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
36. [Gp78, a Membrane-Anchored Ubiquitin Ligase, Associates with Insig-1 and Couples Sterol-Regulated Ubiquitination to Degradation of HMG CoA Reductase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
37. [Identification of SVIP as an Endogenous Inhibitor of Endoplasmic Reticulum-associated Degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
38. [The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKV5&geneProductId=UniProtKB:Q9UKV5)
39. Ensembl Release 99
40. UMLS 2023