# Aurora kinase B

> mammalian protein found in Homo sapiens

**Wikidata**: [Q4822491](https://www.wikidata.org/wiki/Q4822491)  
**Source**: https://4ort.xyz/entity/aurora-kinase-b-q4822491


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2140408)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL415049)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL402548)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL482968)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1090479)
8. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL482767)
9. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q96GD4)
10. Q20641742
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
13. [Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
14. [Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
15. [Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
16. [Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
17. [A novel big protein TPRBK possessing 25 units of TPR motif is essential for the progress of mitosis and cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
18. [Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
19. [Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
20. [Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
21. [Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
22. [VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
23. [Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
24. [Aurora B -TACC1 protein complex in cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
25. [A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
26. [The GAR domain of GAS2L3 mediates binding to the chromosomal passenger complex and is required for localization of GAS2L3 to the constriction zone during abscission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
27. [Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
28. [Cell death in leukemia: passenger protein regulation by topoisomerase inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
29. [Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
30. [Phosphorylation of multifunctional nucleolar protein nucleophosmin (NPM1) by aurora kinase B is critical for mitotic progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
31. [An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
32. [EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
33. [The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
34. [Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
35. [Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
36. [Septin1, a new interaction partner for human serine/threonine kinase aurora-B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
37. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
38. [Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
39. [A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
40. [Aurora A, centrosome structure, and the centrosome cycle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
41. [The chromosomal passenger complex controls the function of endosomal sorting complex required for transport-III Snf7 proteins during cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
42. [Aurora B Regulates Formin mDia3 in Achieving Metaphase Chromosome Alignment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
43. [Aurora A, centrosome structure, and the centrosome cycle](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96GD4&geneProductId=UniProtKB:Q96GD4)
44. [A survivin-ran complex regulates spindle formation in tumor cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96GD4&geneProductId=UniProtKB:Q96GD4)
45. [The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96GD4&geneProductId=UniProtKB:Q96GD4)
46. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96GD4&geneProductId=UniProtKB:Q96GD4)
47. [Phosphorylation at serine 331 is required for Aurora B activation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
48. [A nucleolar protein RRS1 contributes to chromosome congression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
49. [A survivin-ran complex regulates spindle formation in tumor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)
50. [The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4)