# Atrophin 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q4654745](https://www.wikidata.org/wiki/Q4654745)  
**Source**: https://4ort.xyz/entity/atrophin-1-q4654745


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P54259)
3. Q20641742
4. [Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
5. [The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
6. [Atrophin-1, the DRPLA Gene Product, Interacts with Two Families of WW Domain-Containing Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
7. [Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
8. [Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
9. [A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
10. [Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P54259&geneProductId=UniProtKB:P54259)
11. [The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
14. [Abnormal gene product identified in hereditary dentatorubral–pallidoluysian atrophy (DRPLA) brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P54259&geneProductId=UniProtKB:P54259)
16. [Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P54259&geneProductId=UniProtKB:P54259)
17. [Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259)
18. Ensembl Release 99