# ATPase phospholipid transporting 8B1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q4654859](https://www.wikidata.org/wiki/Q4654859)  
**Source**: https://4ort.xyz/entity/atpase-phospholipid-transporting-8b1-q4654859


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O43520)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
5. [ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
6. [Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
7. [Differential effects of progressive familial intrahepatic cholestasis type 1 and benign recurrent intrahepatic cholestasis type 1 mutations on canalicular localization of ATP8B1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
8. [FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43520&geneProductId=UniProtKB:O43520)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43520&geneProductId=UniProtKB:O43520)
10. [FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
12. [Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43520&geneProductId=UniProtKB:O43520)
13. [A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
14. [FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
15. [CDC50A plays a key role in the uptake of the anticancer drug perifosine in human carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
16. [ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43520&geneProductId=UniProtKB:O43520)
17. [CDC50A plays a key role in the uptake of the anticancer drug perifosine in human carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43520&geneProductId=UniProtKB:O43520)
18. [Altered hepatobiliary gene expressions in PFIC1: ATP8B1 gene defect is associated with CFTR downregulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43520)
19. ensembl Release 92
20. Transporter Classification database