# ATPase copper transporting beta

> mammalian protein found in Homo sapiens

**Wikidata**: [Q419611](https://www.wikidata.org/wiki/Q419611)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Wilson_disease_protein)  
**Source**: https://4ort.xyz/entity/atpase-copper-transporting-beta


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P35670)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
6. [ATP7B mediates vesicular sequestration of copper: insight into biliary copper excretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
7. [Functional properties of the human copper-transporting ATPase ATP7B (the Wilson's disease protein) and regulation by metallochaperone Atox1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
8. [Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
9. [Copper-dependent interaction of glutaredoxin with the N termini of the copper-ATPases (ATP7A and ATP7B) defective in Menkes and Wilson diseases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
10. [A new hepatocytic isoform of PLZF lacking the BTB domain interacts with ATP7B, the Wilson disease protein, and positively regulates ERK signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
11. [The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
12. [Metallochaperone Atox1 transfers copper to the NH2-terminal domain of the Wilson's disease protein and regulates its catalytic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
13. [Binding of copper(I) by the Wilson disease protein and its copper chaperone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35670&geneProductId=UniProtKB:P35670)
15. [Solution structure of the N-domain of Wilson disease protein: distinct nucleotide-binding environment and effects of disease mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
16. [The distinct functional properties of the nucleotide-binding domain of ATP7B, the human copper-transporting ATPase: analysis of the Wilson disease mutations E1064A, H1069Q, R1151H, and C1104F](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
17. [Functional characterization of missense mutations in ATP7B: Wilson disease mutation or normal variant?](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35670&geneProductId=UniProtKB:P35670)
18. [Functional characterization of new mutations in Wilson disease gene (ATP7B) using the yeast model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
19. [Functional characterization of missense mutations in ATP7B: Wilson disease mutation or normal variant?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
21. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35670&geneProductId=UniProtKB:P35670)
22. [The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
23. [ATP7B mediates vesicular sequestration of copper: insight into biliary copper excretion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35670&geneProductId=UniProtKB:P35670)
24. [Signals regulating trafficking of Menkes (MNK; ATP7A) copper-translocating P-type ATPase in polarized MDCK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35670&geneProductId=UniProtKB:P35670)
25. [Signals regulating trafficking of Menkes (MNK; ATP7A) copper-translocating P-type ATPase in polarized MDCK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
26. [Copper binding to the N-terminal metal-binding sites or the CPC motif is not essential for copper-induced trafficking of the human Wilson protein (ATP7B)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35670&geneProductId=UniProtKB:P35670)
27. [The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
28. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
29. [Copper binding to the N-terminal metal-binding sites or the CPC motif is not essential for copper-induced trafficking of the human Wilson protein (ATP7B)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
30. [Copper-induced trafficking of the cU-ATPases: a key mechanism for copper homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35670)
31. Ensembl Release 99
32. Identifiers.org
33. UMLS 2023
34. Transporter Classification database