# ATPase copper transporting alpha

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28556980](https://www.wikidata.org/wiki/Q28556980)  
**Source**: https://4ort.xyz/entity/atpase-copper-transporting-alpha


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P70705)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70705&geneProductId=UniProtKB:P70705)
7. [Novel role of copper transport protein antioxidant-1 in neointimal formation after vascular injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
8. [Alternative splicing of the Menkes copper Atpase (Atp7a) transcript in the rat intestinal epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
9. [Mammary gland copper transport is stimulated by prolactin through alterations in Ctr1 and Atp7A localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
10. [Adaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine α-Amidating Monooxygenase, a Luminal Cuproenzyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
11. [NMDA receptor activation mediates copper homeostasis in hippocampal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
12. [Unexpected role of the copper transporter ATP7A in PDGF-induced vascular smooth muscle cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
13. [Menkes protein localization in rat parotid acinar cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
14. [Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
15. [Silencing of the Menkes copper-transporting ATPase (Atp7a) gene increases cyclin D1 protein expression and impairs proliferation of rat intestinal epithelial (IEC-6) cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
16. [Regulation of Copper Transport Crossing Brain Barrier Systems by Cu-ATPases: Effect of Manganese Exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
17. [Menkes Copper ATPase (Atp7a) is a novel metal-responsive gene in rat duodenum, and immunoreactive protein is present on brush-border and basolateral membrane domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
18. [Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
19. [Dynamics of endogenous ATP7A (Menkes protein) in intestinal epithelial cells: copper-dependent redistribution between two intracellular sites](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
20. [Lysyl oxidase and P-ATPase-7A expression during embryonic development in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
21. [Transcriptional regulation of copper metabolism genes in the liver of fetal and neonatal control and iron-deficient rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
22. [Gene chip analyses reveal differential genetic responses to iron deficiency in rat duodenum and jejunum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
23. [Marginal maternal Zn intake in rats alters mammary gland Cu transporter levels and milk Cu concentration and affects neonatal Cu metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
24. [Effects of lead exposure on copper and copper transporters in choroid plexus of rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
25. [Silencing the Menkes copper-transporting ATPase (Atp7a) gene in rat intestinal epithelial (IEC-6) cells increases iron flux via transcriptional induction of ferroportin 1 (Fpn1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
26. [Homocysteine induces cardiac hypertrophy by up-regulating ATP7a expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
27. [Effects of copper supplementation on copper absorption, tissue distribution, and copper transporter expression in an infant rat model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
28. [Mechanism of copper transport at the blood–cerebrospinal fluid barrier: influence of iron deficiency in an in vitro model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
29. [Transcription factors Sp1 and Hif2α mediate induction of the copper-transporting ATPase (Atp7a) gene in intestinal epithelial cells during hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
30. [Perturbation of copper (Cu) homeostasis and expression of Cu-binding proteins in cadmium-resistant lung fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
31. [Copper stabilizes the Menkes copper-transporting ATPase (Atp7a) protein expressed in rat intestinal epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
32. [Involvement of CTR1 and ATP7A in lead (Pb)-induced copper (Cu) accumulation in choroidal epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
33. [Transcriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2α) in intestinal epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70705)
34. ensembl Release 106