ATP binding cassette subfamily G member 2 (Junior blood group)
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: cyclosporine
additional property: PropertyValue
  property ID: P361
  value: ATP-binding cassette subfamily G member 2
additional property: PropertyValue
  property ID: P361
  value: P-loop containing nucleoside triphosphate hydrolase
additional property: PropertyValue
  property ID: P361
  value: Eye Pigment Precursor Transporter
additional property: PropertyValue
  property ID: P527
  value: ABC transporter-like
additional property: PropertyValue
  property ID: P527
  value: ABC-2 type transporter
additional property: PropertyValue
  property ID: P527
  value: AAA+ ATPase domain
additional property: PropertyValue
  property ID: P637
  value: NP_001244315
additional property: PropertyValue
  property ID: P637
  value: NP_004818
additional property: PropertyValue
  property ID: P637
  value: XP_005263412
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: ABC-type xenobiotic transporter activity
additional property: PropertyValue
  property ID: P680
  value: heme transmembrane transporter activity
additional property: PropertyValue
  property ID: P681
  value: mitochondrial membranes
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P682
  value: urate metabolic process
additional property: PropertyValue
  property ID: P682
  value: cellular iron ion homeostasis
additional property: PropertyValue
  property ID: P682
  value: heme transport
additional property: PropertyValue
  property ID: P702
  value: ABCG2
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000237612
additional property: PropertyValue
  property ID: P705
  value: ENSP00000426917
additional property: PropertyValue
  property ID: P705
  value: ENSP00000426916
additional property: PropertyValue
  property ID: P7260
  value: 3.A.1.204.2
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 22
      unique citations norm: 0.009
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 22
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q367700
    source count: 1
    confidence: 0.2
    value label: cyclosporine
  P352:
    value: Q9UNQ0
    source count: 1
    confidence: 0.2
  P361:
    value: Q24769503
    source count: 1
    confidence: 0.2
    value label: ATP-binding cassette subfamily G member 2
  P361:
    value: Q24726930
    source count: 1
    confidence: 0.2
    value label: P-loop containing nucleoside triphosphate hydrolase
  P361:
    value: Q78438089
    source count: 1
    confidence: 0.2
    value label: Eye Pigment Precursor Transporter
  P361:
    value: Q83141907
    source count: 1
    confidence: 0.2
    value label: ABC-2 type transporter, protein family
  P361:
    value: Q4649768
    source count: 1
    confidence: 0.2
    value label: AAA proteins
  P527:
    value: Q24772708
    source count: 1
    confidence: 0.2
    value label: ABC transporter-like
  P527:
    value: Q24774999
    source count: 1
    confidence: 0.2
    value label: ABC-2 type transporter
  P527:
    value: Q24774001
    source count: 1
    confidence: 0.2
    value label: AAA+ ATPase domain
  P637:
    value: NP_001244315
    source count: 1
    confidence: 0.2
  P637:
    value: NP_004818
    source count: 1
    confidence: 0.2
  P637:
    value: XP_005263412
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011530722
    source count: 1
    confidence: 0.2
  P637:
    value: XP_016864341
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14865099
    source count: 1
    confidence: 0.2
    value label: ABC-type xenobiotic transporter activity
  P680:
    value: Q14876663
    source count: 1
    confidence: 0.2
    value label: heme transmembrane transporter activity
  P680:
    value: Q14762996
    source count: 1
    confidence: 0.2
    value label: protein homodimerization activity
  P680:
    value: Q14864384
    source count: 2
    confidence: 0.4
    value label: transporter activity
  P681:
    value: Q14860954
    source count: 1
    confidence: 0.2
    value label: mitochondrial membranes

value: Q14349455
source count: 2
confidence: 0.4
value label: membrane

value: Q39572
source count: 1
confidence: 0.2
value label: mitochondrion

value: Q40260
source count: 1
confidence: 0.2
value label: nucleus

value: Q29548
source count: 3
confidence: 0.6
value label: plasma membrane

value: Q21106285
source count: 3
confidence: 0.6
value label: urate metabolic process

value: Q14820935
source count: 1
confidence: 0.2
value label: cellular iron ion homeostasis

value: Q14876667
source count: 1
confidence: 0.2
value label: heme transport

value: Q14865100
source count: 1
confidence: 0.2
value label: xenobiotic transmembrane transport

value: Q14865106
source count: 1
confidence: 0.2
value label: xenobiotic transport

value: Q4650095
source count: 1
confidence: 0.2
value label: ABCG2

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000237612
source count: 1
confidence: 0.2

value: ENSP00000426917
source count: 1
confidence: 0.2

value: ENSP00000426916
source count: 1
confidence: 0.2

value: ENSP00000426934
source count: 1
confidence: 0.2

value: ENSP00000498246
source count: 1
confidence: 0.2

value: 3.A.1.204.2
source count: 2
confidence: 0.4

source: GOA
stated in qid: Q28018111
retrieved: 2019-05-09

source: A multidrug resistance transporter from human MCF-7 breast cancer cells
stated in qid: Q22008574
retrieved: 2018-01-01

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: Expression and functional characterization of ABCG1 splice variant ABCG1(666)
stated in qid: Q24298066
retrieved: 2019-05-09

source: A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
stated in qid: Q22008526
retrieved: 2018-01-01

source: Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2
stated in qid: Q24316869
retrieved: 2019-05-09

source: The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells
stated in qid: Q24302137
retrieved: 2019-05-09

source: A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
stated in qid: Q22008526
retrieved: 2018-01-31

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2018-09-10

source: The human breast cancer resistance protein (BCRP/ABCG2) shows conformational changes with mitoxantrone
stated in qid: Q40147815
retrieved: 2019-05-09

source: Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
stated in qid: Q34985649
retrieved: 2019-05-09

source: Purification and 3D structural analysis of oligomeric human multidrug transporter ABCG2.
stated in qid: Q41792411
retrieved: 2019-05-09

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2018-01-01

source: Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study
stated in qid: Q24318894
retrieved: 2019-05-09

source: Sex and age interaction with genetic association of atherogenic uric acid concentrations
stated in qid: Q24294258
retrieved: 2019-05-09

source: Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
stated in qid: Q21092458
retrieved: 2019-05-09

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21113683
domain: protein
level: standard
html url: https://4ort.xyz/entity/atp-binding-cassette-subfamily-g-member-2-junior-blood-group-
markdown url: https://4ort.xyz/entity/atp-binding-cassette-subfamily-g-member-2-junior-blood-group-.md
facts url summary: https://4ort.xyz/entity/atp-binding-cassette-subfamily-g-member-2-junior-blood-group-/facts.json
facts url standard: https://4ort.xyz/entity/atp-binding-cassette-subfamily-g-member-2-junior-blood-group-/facts.json
facts url full: https://4ort.xyz/entity/atp-binding-cassette-subfamily-g-member-2-junior-blood-group-/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-02T18:06:50.086396Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:12:18.107337+00:00Z