# ataxin 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q4812916](https://www.wikidata.org/wiki/Q4812916)  
**Source**: https://4ort.xyz/entity/ataxin-1-q4812916


## References

1. UniProt
2. Q20641742
3. [The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
4. [Identification of a self-association region within the SCA1 gene product, ataxin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
6. [p80 coilin, a coiled body-specific protein, interacts with ataxin-1, the SCA1 gene product](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
7. [Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
8. [The role of LANP and ataxin 1 in E4F-mediated transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
9. [Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
10. [USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
11. [RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
12. [A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
13. [Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
14. [A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
15. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
16. [Development and application of a DNA microarray-based yeast two-hybrid system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
17. [Ataxin‐1 and Brother of ataxin‐1 are components of the Notch signalling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
18. [The AXH domain adopts alternative folds the solution structure of HBP1 AXH.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
20. [Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
21. [Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
22. [RNA association and nucleocytoplasmic shuttling by ataxin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
23. [RNA association and nucleocytoplasmic shuttling by ataxin-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P54253&geneProductId=UniProtKB:P54253)
24. [The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54253)
25. [Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P54253&geneProductId=UniProtKB:P54253)
26. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P54253&geneProductId=UniProtKB:P54253)
27. Ensembl Release 99
28. UMLS 2023