# Arrestin beta 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109259](https://www.wikidata.org/wiki/Q21109259)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Arrestin_beta_1)  
**Source**: https://4ort.xyz/entity/arrestin-beta-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P49407)
3. Q20641742
4. [beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
5. [A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
6. [beta-Arrestin: a protein that regulates beta-adrenergic receptor function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
7. [{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
9. [Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
10. [The melanosomal/lysosomal protein OA1 has properties of a G protein-coupled receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
11. [Ubiquitination of CXCR7 controls receptor trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
12. [Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
13. [β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
14. [β-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
15. [β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
16. [Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
17. [A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
18. [A scanning peptide array approach uncovers association sites within the JNK/beta arrestin signalling complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
19. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
20. [Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
21. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
22. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
23. [Role of beta-arrestin 1 in the metastatic progression of colorectal cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
24. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
25. [β-Arrestin-1 directly interacts with Gαs and regulates its function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
26. [Functional specialization of beta-arrestin interactions revealed by proteomic analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
27. [The EHEC-host interactome reveals novel targets for the translocated intimin receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
28. [Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
30. [Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
31. [Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49407&geneProductId=UniProtKB:P49407)
32. [Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
33. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49407&geneProductId=UniProtKB:P49407)
34. [beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
35. [Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
36. [Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
37. [β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49407)
38. Ensembl Release 99
39. UMLS 2023