# Arrestin, beta 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558476](https://www.wikidata.org/wiki/Q28558476)  
**Source**: https://4ort.xyz/entity/arrestin-beta-1-q28558476


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P29066)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
5. [Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
6. [Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
7. [A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
8. [Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
9. [beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
10. [Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
11. [The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
12. [17beta-estradiol-mediated neuroprotection and ERK activation require a pertussis toxin-sensitive mechanism involving GRK2 and beta-arrestin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
13. [Different internalization properties of the alpha1a- and alpha1b-adrenergic receptor subtypes: the potential role of receptor interaction with beta-arrestins and AP50](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
14. [G protein-coupled receptor kinase 2 and beta-arrestins are recruited to FSH receptor in stimulated rat primary Sertoli cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
15. [Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
16. [Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
17. [β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
18. [Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
20. [Differential Regulation of Endosomal GPCR/β-Arrestin Complexes and Trafficking by MAPK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
21. [Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
22. [Role of G protein-coupled receptor kinase 4 and beta-arrestin 1 in agonist-stimulated metabotropic glutamate receptor 1 internalization and activation of mitogen-activated protein kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
23. [Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
24. [Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
25. [PAR-1 activation rescues astrocytes through the PI3K/Akt signaling pathway from chemically induced apoptosis that is exacerbated by gene silencing of β-arrestin 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
26. [Presence of β-arrestin-1 immunoreactivity in the cutaneous nerve fibers of rat glabrous skin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
27. [The induction of thioredoxin-1 by epinephrine withdraws stress via interaction with β-arrestin-1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
28. [{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
29. [Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
30. [A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
31. [An adrenal beta-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29066)
32. ensembl Release 104