# Argininosuccinate synthase 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28557136](https://www.wikidata.org/wiki/Q28557136)  
**Source**: https://4ort.xyz/entity/argininosuccinate-synthase-1-q28557136


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P09034)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
5. [Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
6. [Decreased urea synthesis in cafeteria-diet-induced obesity in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
8. [Identification of fumonisin B1 as an inhibitor of argininosuccinate synthetase using fumonisin affinity chromatography and in vitro kinetic studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
9. [Activated microglia cells express argininosuccinate synthetase and argininosuccinate lyase in the rat brain after transient ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
10. [Argininosuccinate synthetase and argininosuccinate lyase are localized around mitochondria: an immunocytochemical study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
11. [Intracellular localization of HSP73 and HSP90 in rat kidneys with acute lysosomal thesaurismosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
12. [Transient ischemia increases neuronal nitric oxide synthase, argininosuccinate synthetase and argininosuccinate lyase co-expression in rat striatal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
13. [L-citrulline recycling by argininosuccinate synthetase and lyase in rat gastric fundus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
14. [Expression of the genes of arginine-synthesizing enzymes in the rat kidney during development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
15. [Regulation of Argininosuccinate Synthetase mRNA Level in Rat Foetal Hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
16. [Coinduction of nitric oxide synthase and arginine metabolic enzymes in endotoxin-induced uveitis rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
17. [Effect of lipopolysaccharide on in vivo and genetic regulation of rat urea synthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
18. [Arginine-Metabolizing Enzymes in the Developing Rat Small Intestine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
19. [The 'intestinal-renal' arginine biosynthetic axis in the aging rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
20. [Identification of salt-sensitive genes in the kidneys of Dahl rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
21. [Urea cycle gene expression is suppressed by PFOA treatment in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
22. [Nitrogen detoxification in artificially-fed zinc-deficient rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
23. [Modulation of intestinal urea cycle by dietary spermine in suckling rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
24. [Estrogen regulation of the rat anterior pituitary gland proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
25. [Induction of citrulline-nitric oxide (NO) cycle enzymes and NO production in immunostimulated rat RPE-J cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
26. [Maternal supplementation with citrulline increases renal nitric oxide in young spontaneously hypertensive rats and has long-term antihypertensive effects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
27. [Effects of growth hormone on steroid-induced increase in ability of urea synthesis and urea enzyme mRNA levels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
28. [Induction of astrocyte argininosuccinate synthetase and argininosuccinate lyase by dibutyryl cyclic AMP and dexamethasone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
29. [Ontogenesis of Nitric Oxide Synthases in the Ventilatory Muscles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
30. [Identification of novel protein targets regulated by maternal dietary fatty acid composition in neonatal rat liver.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
31. [Inability of rat alveolar macrophages to recycle L-citrulline to L-arginine despite induction of argininosuccinate synthetase mRNA and protein, and inhibition of nitric oxide synthesis by exogenous L-citrulline](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
32. [Glutamine and regulation of gene expression in rat hepatocytes: the role of cell swelling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
33. [Hyperammonemia: regulation of argininosuccinate synthetase and argininosuccinate lyase genes in aggregating cell cultures of fetal rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
34. [Coinduction of inducible nitric oxide synthase and arginine recycling enzymes in cytokine-stimulated PC12 cells and high output production of nitric oxide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
35. [Long-chain fatty acids suppress the induction of urea cycle enzyme genes by glucocorticoid action](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
36. [Polyaspartoyl.l-arginine inhibits platelet aggregation through stimulation of NO release from endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09034)
37. ensembl Release 106