Arginase type II
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: O08691
additional property: PropertyValue
  property ID: P361
  value: Ureohydrolase domain superfamily
additional property: PropertyValue
  property ID: P361
  value: arginase
additional property: PropertyValue
  property ID: P361
  value: Ureohydrolase, manganese-binding site, protein family
additional property: PropertyValue
  property ID: P527
  value: Ureohydrolase, manganese-binding site
additional property: PropertyValue
  property ID: P637
  value: NP_033835
additional property: PropertyValue
  property ID: P680
  value: hydrolase activity
additional property: PropertyValue
  property ID: P680
  value: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P682
  value: striated muscle contraction
additional property: PropertyValue
  property ID: P682
  value: ureteric bud development
additional property: PropertyValue
  property ID: P682
  value: urea cycle
additional property: PropertyValue
  property ID: P702
  value: Arg2
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000021550
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 19
      unique citations norm: 0.007
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 19
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: O08691
    source count: 1
    confidence: 0.2
  P361:
    value: Q41796664
    source count: 1
    confidence: 0.2
    value label: Ureohydrolase domain superfamily
  P361:
    value: Q24721374
    source count: 1
    confidence: 0.2
    value label: arginase
  P361:
    value: Q95354725
    source count: 1
    confidence: 0.2
    value label: Ureohydrolase, manganese-binding site, protein family
  P527:
    value: Q24782592
    source count: 1
    confidence: 0.2
    value label: Ureohydrolase, manganese-binding site
  P637:
    value: NP_033835
    source count: 1
    confidence: 0.2
  P680:
    value: Q14353168
    source count: 1
    confidence: 0.2
    value label: hydrolase activity
  P680:
    value: Q21114555
    source count: 1
    confidence: 0.2
    value label: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
  P680:
    value: Q13667380
    source count: 2
    confidence: 0.4
    value label: metal ion binding
  P680:
    value: Q21101885
    source count: 4
    confidence: 0.8
    value label: arginase activity
  P680:
    value: Q21101885
    source count: 5
    confidence: 1.0
    value label: arginase activity
  P681:
    value: Q39572
    source count: 5
    confidence: 1.0
    value label: mitochondrion
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q39572
    source count: 6
    confidence: 1.0
    value label: mitochondrion
  P682:
    value: Q14865088
    source count: 1
    confidence: 0.2
    value label: striated muscle contraction
  P682:
    value: Q14819652
    source count: 1
    confidence: 0.2
    value label: ureteric bud development
  P682:
    value: Q595994
    source count: 1
    confidence: 0.2
    value label: urea cycle
  P682:
    value: Q21101889
    source count: 2
    confidence: 0.4
    value label: arginine metabolic process
  P682:
    value: Q14907231
    source count: 1
    confidence: 0.2
    value label: negative regulation of type 2 immune response
  P702:
    value: Q18247808
    source count: 1
    confidence: 0.2
    value label: Arg2
  P703:
    value: Q83310
    source count: 1
    confidence: 0.2
    value label: house mouse
  P705:
    value: ENSMUSP00000021550
    source count: 1
    confidence: 0.2
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-02-14

source: Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism
stated in qid: Q28576858
retrieved: 2017-10-31

source: GOA
stated in qid: Q28018111
retrieved: 2017-10-31

source: Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism
stated in qid: Q28576858
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation.
stated in qid: Q40036309
retrieved: 2017-10-31

source: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
stated in qid: Q28593536
retrieved: 2017-10-31

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2017-10-31

source: Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation.
stated in qid: Q40036309
retrieved: 2019-02-14

source: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
stated in qid: Q28593536
retrieved: 2019-02-14

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2019-02-14

source: Spatial gene expression in the T-stage mouse metanephros
stated in qid: Q28585064
retrieved: 2019-02-14

source: Increased mitochondrial arginine metabolism supports bioenergetics in asthma
stated in qid: Q37042318
retrieved: 2019-02-14

source: Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection.
stated in qid: Q39853759
retrieved: 2019-02-14

source: L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
stated in qid: Q37359052
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21984970
domain: protein
level: standard
html url: https://4ort.xyz/entity/arginase-type-ii
markdown url: https://4ort.xyz/entity/arginase-type-ii.md
facts url summary: https://4ort.xyz/entity/arginase-type-ii/facts.json
facts url standard: https://4ort.xyz/entity/arginase-type-ii/facts.json
facts url full: https://4ort.xyz/entity/arginase-type-ii/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-19T02:50:49.164820Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:57:29.049494+00:00Z