# Arachidonate 5-lipoxygenase

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558027](https://www.wikidata.org/wiki/Q28558027)  
**Source**: https://4ort.xyz/entity/arachidonate-5-lipoxygenase-q28558027


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P12527)
3. Q20641742
4. [Lipoxygenase-dependent superoxide release in skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12527&geneProductId=UniProtKB:P12527)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12527&geneProductId=UniProtKB:P12527)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
7. [The nuclear membrane organization of leukotriene synthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
8. [Activation of 5-lipoxygenase after oxygen-glucose deprivation is partly mediated via NMDA receptor in rat cortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
9. [Increased expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase-activating protein in rat peritoneal macrophages during ovalbumin-induced sensitization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
10. [Lipoxygenase-dependent superoxide release in skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
11. [Zileuton Reduces Inflammatory Reaction and Brain Damage Following Permanent Cerebral Ischemia in Rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
12. [Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
13. [CJ-13610, an orally active inhibitor of 5-lipoxygenase is efficacious in preclinical models of pain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
14. [Isolation and characterization of a cDNA clone encoding rat 5-lipoxygenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
15. [Effect of 5-lipoxygenase blockade on blood pressure and acetylcholine-evoked endothelium-dependent contraction in aorta from spontaneously hypertensive rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
16. [Hyperoxia increases protein mass of 5-lipoxygenase and its activating protein, flap, and leukotriene B(4) output in newborn rat lungs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12527)
17. ensembl Release 106