# Arachidonate 12-lipoxygenase, 12S type

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21133173](https://www.wikidata.org/wiki/Q21133173)  
**Source**: https://4ort.xyz/entity/arachidonate-12-lipoxygenase-12s-type-q21133173


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P18054)
3. [Swiss-Prot](http://www.uniprot.org/uniprot/P18054.txt?version=173)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
7. [Catalytic properties of human platelet 12-lipoxygenase as compared with the enzymes of other origins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
8. [Purification and characterization of recombinant histidine-tagged human platelet 12-lipoxygenase expressed in a baculovirus/insect cell system](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
9. [Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
10. [Cloning of the cDNA for human 12-lipoxygenase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
11. [Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
12. [Purification and characterization of recombinant histidine-tagged human platelet 12-lipoxygenase expressed in a baculovirus/insect cell system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
13. [Catalytic properties of human platelet 12-lipoxygenase as compared with the enzymes of other origins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
14. [Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
15. [Cloning of the cDNA for human 12-lipoxygenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
16. [Lipoxygenase-dependent superoxide release in skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
17. [12-Lipoxygenase in A431 cells: genetic identity, modulation of expression, and intracellular localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
18. [Lipoxygenase-dependent superoxide release in skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
19. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
20. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
21. [Lipoxin synthase activity of human platelet 12-lipoxygenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
22. [Up-regulation of 12(S)-lipoxygenase induces a migratory phenotype in colorectal cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
23. [Molecular identification, localization and function of platelet-type 12-lipoxygenase in human melanoma progression, under experimental and clinical conditions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
24. [12S-Lipoxygenase is necessary for human vascular smooth muscle cell survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
25. [Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
26. [Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
27. [Relationship between lipoxygenase and human testicular cancer](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
28. [12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18054)
29. [Expression of lipoxygenase in human prostate cancer and growth reduction by its inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
30. [Increased metastatic potential in human prostate carcinoma cells by overexpression of arachidonate 12-lipoxygenase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18054&geneProductId=UniProtKB:P18054)
31. Ensembl Release 99