# Aquaporin 2

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28557356](https://www.wikidata.org/wiki/Q28557356)  
**Source**: https://4ort.xyz/entity/aquaporin-2-q28557356


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P34080)
3. Q20641742
4. [Water channel aquaporin-2 directly binds to actin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
5. [Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
6. [Heat shock protein 70 interacts with aquaporin-2 and regulates its trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
7. [Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
8. [Aquaporin-2 transcript is differentially regulated by dietary salt in Sprague-Dawley and Dahl SS/Jr rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
11. [Aquaporin-2 trafficking is regulated by PDZ-domain containing protein SPA-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
12. [AKAP220 colocalizes with AQP2 in the inner medullary collecting ducts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
13. [Indomethacin enhances shuttling of aquaporin-2 despite decreased abundance in rat kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
14. [Serine 269 phosphorylated aquaporin-2 is targeted to the apical membrane of collecting duct principal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
15. [Large scale protein identification in intracellular aquaporin-2 vesicles from renal inner medullary collecting duct](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
16. [Expression of aquaporin water channels in rat taste buds](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
17. [Regulation of the basolateral chloride/base exchangers AE1 and SLC26A7 in the kidney collecting duct in potassium depletion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
18. [Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
19. [Aquaporin-2, a regulated water channel, is expressed in apical membranes of rat distal colon epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
20. [Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
21. [Identification of a multiprotein "motor" complex binding to water channel aquaporin-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
22. [Role of AQP2 in activation of calcium entry by hypotonicity: implications in cell volume regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
23. [Role of AQP2 during apoptosis in cortical collecting duct cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
24. [Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
25. [Hemodynamic parameters during normal and hypertensive pregnancy in rats: evaluation of renal salt and water transporters](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
26. [Aquaporin-2 downregulation in kidney medulla of aging rats is posttranscriptional and is abolished by water deprivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
27. [Long-term aldosterone treatment induces decreased apical but increased basolateral expression of AQP2 in CCD of rat kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
28. [Potential role of purinergic signaling in lithium-induced nephrogenic diabetes insipidus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
29. [Reciprocal interaction with G-actin and tropomyosin is essential for aquaporin-2 trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
30. [Modulation of aquaporin-2/vasopressin2 receptor kidney expression and tubular injury after endotoxin (lipopolysaccharide) challenge](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
31. [Aquaporin 2 expression increased by glucagon in normal rat inner medullary collecting ducts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
32. [Vasopressin-independent regulation of collecting duct aquaporin-2 in food deprivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34080)
33. ensembl Release 106