# Aquaporin 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q2083074](https://www.wikidata.org/wiki/Q2083074)  
**Source**: https://4ort.xyz/entity/aquaporin-1


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P29972)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
7. [Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
8. [Aquaporin-1 transports NO across cell membranes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
9. [Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
10. [Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
11. [Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
12. [Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
13. [AQP1 is not only a water channel: it contributes to cell migration through Lin7/beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
14. [Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
15. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
16. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
17. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
18. [An empirical framework for binary interactome mapping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
19. [Shifted Transversal Design smart-pooling for high coverage interactome mapping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972)
20. [Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
21. [Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
22. [Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
23. [Functional analysis of aquaporin-1 deficient red cells. The Colton-null phenotype](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
24. [Transmembrane water influx via aquaporin-1 is inhibited by barbiturates and propofol in red blood cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
25. [Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
26. [Glycerol permeability of mutant aquaporin 1 and other AQP-MIP proteins: inhibition studies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
27. [Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
28. [Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
29. [Evidence for a glycerol pathway through aquaporin 1 (CHIP28) channels](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
30. [MEK/ERK pathway mediates UVB-induced AQP1 downregulation and water permeability impairment in human retinal pigment epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
31. [Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
32. [Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
33. [Functional characterization and localization of AQP3 in the human colon](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
34. [Functional characterization of human aquaporin 9 as a facilitative glycerol carrier.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
35. [Aquaporin-1, nothing but a water channel.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
36. [Functional impairment of lens aquaporin in two families with dominantly inherited cataracts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
37. [Novel variants in human Aquaporin-4 reduce cellular water permeability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
38. [Mechanism of selectivity in aquaporins and aquaglyceroporins.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
39. [Water permeability and characterization of aquaporin-11.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
40. [Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
41. [Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
42. [Molecular Cloning and Expression of a Novel Human Aquaporin from Adipose Tissue with Glycerol Permeability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
43. [Mercury-Sensitive Residues and Pore Site in AQP3 Water Channel](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
44. [Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
45. [The subcellular localization of an aquaporin-2 tetramer depends on the stoichiometry of phosphorylated and nonphosphorylated monomers](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
46. [Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
47. [Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
48. [Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
49. [Structural determinants of water permeation through aquaporin-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)
50. [Functional and molecular characterization of the human neutral solute channel aquaporin-9.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972)