# Aquaporin 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14905246](https://www.wikidata.org/wiki/Q14905246)  
**Source**: https://4ort.xyz/entity/aquaporin-1-q14905246


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q02013)
3. Q20641742
4. [Homeostatic maintenance of pathogen-containing vacuoles requires TBK1-dependent regulation of aquaporin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
5. [mRNAs encoding aquaporins are present during murine preimplantation development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02013&geneProductId=UniProtKB:Q02013)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02013&geneProductId=UniProtKB:Q02013)
7. [EphB2 guides axons at the midline and is necessary for normal vestibular function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
9. [Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
11. [mRNAs encoding aquaporins are present during murine preimplantation development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
12. [Identification and characterization of an aquaporin 1 immunoreactive amacrine-type cell of the mouse retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
13. [Aquaporin 1 is important for maintaining secretory granule biogenesis in endocrine cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
14. [Aquaporin-1 in the choroid plexuses of developing mammalian brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
15. [Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
16. [Very high aquaporin-1 facilitated water permeability in mouse gallbladder](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
17. [Aquaporin-1 in cardiac endothelial cells is downregulated in ischemia, hypoxia and cardioplegia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
18. [Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02013&geneProductId=UniProtKB:Q02013)
19. [Anatomical and functional analysis of aquaporin 1, a water channel in primary afferent neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
20. [The water channel aquaporin-1 partitions into exosomes during reticulocyte maturation: implication for the regulation of cell volume](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
21. [Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
22. [Analysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
23. [Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
24. [Role of aquaporin water channels in pleural fluid dynamics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
25. [Functional expression of aquaporins in embryonic, postnatal, and adult mouse lenses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
26. [Aquaporin-1 in the choroid plexuses of developing mammalian brain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02013&geneProductId=UniProtKB:Q02013)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02013&geneProductId=UniProtKB:Q02013)
28. [Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
29. [Use of dual section mRNA in situ hybridisation/immunohistochemistry to clarify gene expression patterns during the early stages of nephron development in the embryo and in the mature nephron of the adult mouse kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
30. [Phenotype analysis of aquaporin-8 null mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
31. [Role of aquaporin-4 in airspace-to-capillary water permeability in intact mouse lung measured by a novel gravimetric method](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
32. [Role of aquaporin and sodium channel in pleural water movement](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
33. [Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
34. [Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
35. [Effect of aquaporin-1 deletion on pleural fluid transport](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
36. [Luminal hypotonicity in proximal tubules of aquaporin-1-knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
37. [Erythrocyte water permeability and renal function in double knockout mice lacking aquaporin-1 and aquaporin-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
38. [Accelerated cataract formation and reduced lens epithelial water permeability in aquaporin-1-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
39. [Requirement of aquaporin-1 for NaCl-driven water transport across descending vasa recta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
40. [Compensation of proximal tubule malabsorption in AQP1-deficient mice without TGF-mediated reduction of GFR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
41. [Aquaporin-1-facilitated keratocyte migration in cell culture and in vivo corneal wound healing models](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
42. [Aquaporin deletion in mice reduces intraocular pressure and aqueous fluid production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
43. [Impaired pain sensation in mice lacking Aquaporin-1 water channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
44. [Urea and urine concentrating ability in mice lacking AQP1 and AQP3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
45. [Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
46. [Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
47. [Aquaporin-4 is expressed in basolateral membranes of proximal tubule S3 segments in mouse kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
48. [Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
49. [Partial correction of the urinary concentrating defect in aquaporin-1 null mice by adenovirus-mediated gene delivery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)
50. [Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02013)