# Apoptotic peptidase activating factor 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28562509](https://www.wikidata.org/wiki/Q28562509)  
**Source**: https://4ort.xyz/entity/apoptotic-peptidase-activating-factor-1-q28562509


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9EPV5)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
5. [Huntingtin-interacting protein 1-mediated neuronal cell death occurs through intrinsic apoptotic pathways and mitochondrial alterations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
7. [Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
8. [Jun kinase delays caspase-9 activation by interaction with the apoptosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
9. [The protective effects of tadalafil on renal damage following ischemia reperfusion injury in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
10. [MicroRNA-17-mediated down-regulation of apoptotic protease activating factor 1 attenuates apoptosome formation and subsequent apoptosis of cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
11. [Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
12. [Expression of Cyt-c-Mediated Mitochondrial Apoptosis-Related Proteins in Rat Renal Proximal Tubules during Development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
13. [Alteration of apoptotic protease-activating factor-1 (APAF-1)-dependent apoptotic pathway during development of rat brain and liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
14. [Identification of the apoptosis activation cascade induced in mammary carcinomas by energy restriction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
15. [Modulation of cellular apoptosis with apoptotic protease-activating factor 1 (Apaf-1) inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
16. [Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
17. [Transforming growth factor-beta(1) induces apoptosis in rat FaO hepatoma cells via cytochrome c release and oligomerization of Apaf-1 to form a approximately 700-kd apoptosome caspase-processing complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPV5)
18. ensembl Release 106