# Apoptotic peptidase activating factor 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981465](https://www.wikidata.org/wiki/Q21981465)  
**Source**: https://4ort.xyz/entity/apoptotic-peptidase-activating-factor-1-q21981465


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O88879)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
5. [Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88879&geneProductId=UniProtKB:O88879)
6. [Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
7. [Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88879&geneProductId=UniProtKB:O88879)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88879&geneProductId=UniProtKB:O88879)
11. [Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
12. [Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88879&geneProductId=UniProtKB:O88879)
13. [Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88879&geneProductId=UniProtKB:O88879)
14. [Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
15. [Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
16. [Apaf-1 deficiency and neural tube closure defects are found in fog mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
17. [Forebrain overgrowth (fog): A new mutation in the mouse affecting neural tube development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
18. [Apaf1 is required for mitochondrial pathways of apoptosis and brain development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
19. [Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
20. [Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
21. [Proapoptotic BAX and BAK control multiple initiator caspases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88879)
22. ensembl Release 106