# Apolipoprotein A1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q1316030](https://www.wikidata.org/wiki/Q1316030)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Apolipoprotein_AI)  
**Source**: https://4ort.xyz/entity/apolipoprotein-a1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P02647)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
6. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
7. [Apolipoprotein specificity for lipid efflux by the human ABCAI transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
8. [Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
9. [Apolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptake](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
10. [A protein cofactor of lecithin:cholesterol acyltransferase](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
11. [Structure and interfacial properties of human apolipoprotein A-V](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
12. [Apolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
13. [Interaction of rat lecithin-cholesterol acyltransferase with rat apolipoprotein A-I and with lecithin-cholesterol vesicles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
14. [A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
15. [Enhanced Cholesterol Efflux by Tyrosyl Radical-oxidized High Density Lipoprotein Is Mediated by Apolipoprotein AI-AII Heterodimers](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
16. [Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
17. [Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
18. [The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
19. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
20. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
21. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
22. [An investigation into the human serum "interactome"](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
23. [Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
24. [Haptoglobin binds the antiatherogenic protein apolipoprotein E - impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
25. [The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
26. [Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
27. [ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
28. [Apolipoprotein(a) acts as a chemorepellent to human vascular smooth muscle cells via integrin αVβ3 and RhoA/ROCK-mediated mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
29. [Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
30. [Amyloidogenic mutations in human apolipoprotein A-I are not necessarily destabilizing - a common mechanism of apolipoprotein A-I misfolding in familial amyloidosis and atherosclerosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
31. [The extreme N-terminal region of human apolipoprotein A-I has a strong propensity to form amyloid fibrils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
32. [Identification of an amyloid fibril forming peptide comprising residues 46-59 of apolipoprotein A-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
33. [Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein A-I.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
34. [Structural and functional properties of human and mouse apolipoprotein A-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
35. [Association of human, rat, and rabbit apolipoprotein E with ?-amyloid](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
36. [Structure and interfacial properties of human apolipoprotein A-V](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
37. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
38. [A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
39. [Enhanced Cholesterol Efflux by Tyrosyl Radical-oxidized High Density Lipoprotein Is Mediated by Apolipoprotein AI-AII Heterodimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
40. [Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
41. [A protein cofactor of lecithin:cholesterol acyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
42. [Apolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptake](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
43. [Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
44. [TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
45. [Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
46. [Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02647)
47. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
48. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
49. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)
50. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02647)