# Apolipoprotein A-I

> mammalian protein found in Mus musculus

**Wikidata**: [Q14910072](https://www.wikidata.org/wiki/Q14910072)  
**Source**: https://4ort.xyz/entity/apolipoprotein-a-i


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q00623)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
7. [Structural and functional properties of human and mouse apolipoprotein A-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
8. [Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623)
9. [RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
10. [Intracellular lipidation of newly synthesized apolipoprotein A-I in primary murine hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
11. [A protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
12. [Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
13. [Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
14. [Influence of apoA-I and apoE on the formation of serum amyloid A-containing lipoproteins in vivo and in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
15. [Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
16. [Genetic control of lipid transport in mice. II. Genes controlling structure of high density lipoproteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
17. [ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
18. [Effect of apolipoprotein A-I deficiency on lecithin:cholesterol acyltransferase activation in mouse plasma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
19. [Delayed loss of cholesterol from a localized lipoprotein depot in apolipoprotein A-I-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
20. [Abnormal phospholipid composition impairs HDL biogenesis and maturation in mice lacking Abca1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
21. [ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
22. [SAA-only HDL formed during the acute phase response in apoA-I+/+ and apoA-I-/- mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
23. [Dietary fatty acids and dietary cholesterol differ in their effect on the in vivo regulation of apolipoprotein A-I and A-II gene expression in inbred strains of mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
24. [Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
25. [Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
26. [Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623)
27. [Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
28. [Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
29. [Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
30. [ApoA1 reduces free cholesterol accumulation in atherosclerotic lesions of ApoE-deficient mice transplanted with ApoE-expressing macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
31. [High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
32. [Point mutations in apolipoprotein A-I mimic the phenotype observed in patients with classical lecithin:cholesterol acyltransferase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
33. [Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
34. [The acute phase response in apolipoprotein A-1 knockout mice: apolipoprotein serum amyloid A and lipid distribution in plasma high density lipoproteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
35. [HDL Deficiency in Genetically Engineered Mice Requires Elevated LDL to Accelerate Atherogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
36. [ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
37. [Inflammation and skin cholesterol in LDLr-/-, apoA-I-/- mice: link between cholesterol homeostasis and self-tolerance?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
38. [Delayed loss of cholesterol from a localized lipoprotein depot in apolipoprotein A-I-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623)
39. [Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623)
40. [Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623)
41. [ApoA-I knockout mice: characterization of HDL metabolism in homozygotes and identification of a post-RNA mechanism of apoA-I up-regulation in heterozygotes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623)
42. [Apolipoprotein E and Apolipoprotein A-1 Knock-Out Mice Readily Develop Amyloid A Protein Amyloidosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
43. [Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
44. [Kinetic characteristics and regulation of HDL cholesteryl ester and apolipoprotein transport in the apoA-I-/- mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00623)
45. [Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00623&geneProductId=UniProtKB:Q00623)
46. ensembl Release 106