Anoctamin 2
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Anoctamin-2
additional property: PropertyValue
  property ID: P361
  value: Calcium-dependent chloride channel
additional property: PropertyValue
  property ID: P361
  value: Anoctamin, dimerisation domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Anoctamin, dimerisation domain
additional property: PropertyValue
  property ID: P637
  value: NP_001265525
additional property: PropertyValue
  property ID: P637
  value: NP_001265526
additional property: PropertyValue
  property ID: P637
  value: XP_011519277
additional property: PropertyValue
  property ID: P680
  value: protein dimerization activity
additional property: PropertyValue
  property ID: P680
  value: protein homodimerization activity
additional property: PropertyValue
  property ID: P680
  value: chloride channel activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: ion transmembrane transport
additional property: PropertyValue
  property ID: P682
  value: chloride transport
additional property: PropertyValue
  property ID: P682
  value: ion transport
additional property: PropertyValue
  property ID: P702
  value: ANO2
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000314048
additional property: PropertyValue
  property ID: P705
  value: ENSP00000348453
additional property: PropertyValue
  property ID: P705
  value: ENSP00000440981
additional property: PropertyValue
  property ID: P7260
  value: 1.A.17.1.3
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 12
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 12
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9NQ90
    source count: 1
    confidence: 0.2
  P361:
    value: Q41796819
    source count: 1
    confidence: 0.2
    value label: Anoctamin-2
  P361:
    value: Q25323947
    source count: 1
    confidence: 0.2
    value label: Calcium-dependent chloride channel
  P361:
    value: Q83164573
    source count: 1
    confidence: 0.2
    value label: Anoctamin, dimerisation domain, protein family
  P527:
    value: Q24780302
    source count: 1
    confidence: 0.2
    value label: Anoctamin, dimerisation domain
  P637:
    value: NP_001265525
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001265526
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011519277
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011519280
    source count: 1
    confidence: 0.2
  P637:
    value: XP_016875161
    source count: 1
    confidence: 0.2
  P680:
    value: Q14861864
    source count: 1
    confidence: 0.2
    value label: protein dimerization activity
  P680:
    value: Q14762996
    source count: 1
    confidence: 0.2
    value label: protein homodimerization activity
  P680:
    value: Q14864705
    source count: 1
    confidence: 0.2
    value label: chloride channel activity
  P680:
    value: Q14762999
    source count: 1
    confidence: 0.2
    value label: protein heterodimerization activity
  P680:
    value: Q21100824
    source count: 4
    confidence: 0.8
    value label: intracellular calcium activated chloride channel activity
  P681:
    value: Q14327652
    source count: 1
    confidence: 0.2
    value label: integral component of membrane
  P681:
    value: Q29548
    source count: 5
    confidence: 1.0
    value label: plasma membrane
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q14864703
    source count: 1
    confidence: 0.2
    value label: chloride channel complex
  P681:
    value: Q14817956
    source count: 1
    confidence: 0.2
    value label: nucleoplasm
  P682:
    value: Q14865154
    source count: 1
    confidence: 0.2
    value label: ion transmembrane transport
  P682:
    value: Q14864717
    source count: 2
    confidence: 0.4
    value label: chloride transport
  P682:
    value: Q14859673
    source count: 1
    confidence: 0.2
    value label: ion transport

value: Q15333422
source count: 1
confidence: 0.2
value label: chloride transmembrane transport

value: Q18042886
source count: 1
confidence: 0.2
value label: ANO2

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000314048
source count: 1
confidence: 0.2

value: ENSP00000348453
source count: 1
confidence: 0.2

value: ENSP00000440981
source count: 1
confidence: 0.2

value: ENSP00000443813
source count: 1
confidence: 0.2

value: ENSP00000481449
source count: 1
confidence: 0.2

value: 1.A.17.1.3
source count: 2
confidence: 0.4

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-11-07

source: TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals
stated in qid: Q24314645
retrieved: 2018-11-07

source: The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels
stated in qid: Q24292846
retrieved: 2018-11-07

source: Proteome-wide analysis of phospho-regulated PDZ domain interactions
stated in qid: Q56888773
retrieved: 2019-04-08

source: TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals
stated in qid: Q24314645
retrieved: 2019-04-08

source: The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels
stated in qid: Q24292846
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21105213
domain: protein
level: standard
html url: https://4ort.xyz/entity/anoctamin-2
markdown url: https://4ort.xyz/entity/anoctamin-2.md
facts url summary: https://4ort.xyz/entity/anoctamin-2/facts.json
facts url standard: https://4ort.xyz/entity/anoctamin-2/facts.json
facts url full: https://4ort.xyz/entity/anoctamin-2/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T06:34:44.622141Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:40:42.669745+00:00Z