Ankyrin 1
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P16157
additional property: PropertyValue
  property ID: P361
  value: Death-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Ankyrin repeat-containing domain superfamily
additional property: PropertyValue
  property ID: P361
  value: auxiliary protein involved in transmembrane transport
additional property: PropertyValue
  property ID: P527
  value: ZU5 domain
additional property: PropertyValue
  property ID: P527
  value: ankyrin repeat-containing domain
additional property: PropertyValue
  property ID: P527
  value: death domain
additional property: PropertyValue
  property ID: P637
  value: NP_000028
additional property: PropertyValue
  property ID: P637
  value: NP_001135917
additional property: PropertyValue
  property ID: P637
  value: NP_001135918
additional property: PropertyValue
  property ID: P638
  value: 1N11
additional property: PropertyValue
  property ID: P638
  value: 2YQF
additional property: PropertyValue
  property ID: P638
  value: 2YVI
additional property: PropertyValue
  property ID: P680
  value: spectrin binding
additional property: PropertyValue
  property ID: P680
  value: ATPase binding
additional property: PropertyValue
  property ID: P680
  value: structural molecule activity
additional property: PropertyValue
  property ID: P681
  value: M band
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P681
  value: postsynaptic membrane
additional property: PropertyValue
  property ID: P682
  value: positive regulation of organelle organization
additional property: PropertyValue
  property ID: P682
  value: endoplasmic reticulum to Golgi vesicle-mediated transport
additional property: PropertyValue
  property ID: P682
  value: maintenance of epithelial cell apical/basal polarity
additional property: PropertyValue
  property ID: P702
  value: ANK1
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000265709
additional property: PropertyValue
  property ID: P705
  value: ENSP00000289734
additional property: PropertyValue
  property ID: P705
  value: ENSP00000297744
additional property: PropertyValue
  property ID: P7260
  value: 8.A.28.1.2
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 19
      unique citations norm: 0.007
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 19
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P16157
    source count: 1
    confidence: 0.2
  P361:
    value: Q24776395
    source count: 1
    confidence: 0.2
    value label: Death-like domain superfamily
  P361:
    value: Q41797869
    source count: 1
    confidence: 0.2
    value label: Ankyrin repeat-containing domain superfamily
  P361:
    value: Q67141865
    source count: 1
    confidence: 0.2
    value label: auxiliary protein involved in transmembrane transport
  P361:
    value: Q83146468
    source count: 1
    confidence: 0.2
    value label: Ankyrin repeat-containing domain, protein family
  P361:
    value: Q83130368
    source count: 1
    confidence: 0.2
    value label: Death domain, protein family
  P527:
    value: Q24773892
    source count: 1
    confidence: 0.2
    value label: ZU5 domain
  P527:
    value: Q24778891
    source count: 1
    confidence: 0.2
    value label: ankyrin repeat-containing domain
  P527:
    value: Q5247322
    source count: 1
    confidence: 0.2
    value label: death domain
  P527:
    value: Q24784174
    source count: 1
    confidence: 0.2
    value label: ankyrin repeat
  P637:
    value: NP_000028
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001135917
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001135918
    source count: 1
    confidence: 0.2
  P637:
    value: NP_065208
    source count: 1
    confidence: 0.2
  P637:
    value: NP_065209
    source count: 1
    confidence: 0.2
  P638:
    value: 1N11
    source count: 1
    confidence: 0.2
  P638:
    value: 2YQF
    source count: 1
    confidence: 0.2
  P638:
    value: 2YVI
    source count: 1
    confidence: 0.2
  P638:
    value: 3F59
    source count: 1
    confidence: 0.2
  P638:
    value: 3KBT
    source count: 1
    confidence: 0.2

value: Q14876819
source count: 3
confidence: 0.6
value label: spectrin binding

value: Q14873897
source count: 1
confidence: 0.2
value label: ATPase binding

value: Q14864149
source count: 1
confidence: 0.2
value label: structural molecule activity

value: Q14864144
source count: 1
confidence: 0.2
value label: structural constituent of cytoskeleton

value: Q167149
source count: 5
confidence: 1.0
value label: protein binding

value: Q22330333
source count: 2
confidence: 0.4
value label: M band

value: Q220599
source count: 1
confidence: 0.2
value label: cytosol

value: Q14864257
source count: 1
confidence: 0.2
value label: postsynaptic membrane

value: Q14349455
source count: 1
confidence: 0.2
value label: membrane

value: Q29548
source count: 4
confidence: 0.8
value label: plasma membrane

value: Q21097225
source count: 1
confidence: 0.2
value label: positive regulation of organelle organization

value: Q14882482
source count: 2
confidence: 0.4
value label: endoplasmic reticulum to Golgi vesicle-mediated transport

value: Q21097226
source count: 1
confidence: 0.2
value label: maintenance of epithelial cell apical/basal polarity

value: Q14864151
source count: 1
confidence: 0.2
value label: cytoskeleton organization

value: Q828130
source count: 1
confidence: 0.2
value label: signal transduction

value: Q17826035
source count: 1
confidence: 0.2
value label: ANK1

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000265709
source count: 1
confidence: 0.2

value: ENSP00000289734
source count: 1
confidence: 0.2

value: ENSP00000297744
source count: 1
confidence: 0.2

value: ENSP00000319123
source count: 1
confidence: 0.2

value: ENSP00000339620
source count: 1
confidence: 0.2

value: 8.A.28.1.2
source count: 2
confidence: 0.4

source: Ankyrin-1 mutations are a major cause of dominant and recessive hereditary spherocytosis
stated in qid: Q24313340
retrieved: 2018-03-27

source: Ankyrin binds to two distinct cytoplasmic domains of Na,K-ATPase alpha subunit
stated in qid: Q24310792
retrieved: 2018-03-27

source: The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes
stated in qid: Q24299885
retrieved: 2018-03-27

source: An Alternate Promoter Directs Expression of a Truncated, Muscle-specific Isoform of the Human Ankyrin 1 Gene
stated in qid: Q24321214
retrieved: 2018-03-27

source: Functional interaction between Rh proteins and the spectrin-based skeleton in erythroid and epithelial cells
stated in qid: Q24312849
retrieved: 2018-03-27

source: Rh-RhAG/ankyrin-R, a new interaction site between the membrane bilayer and the red cell skeleton, is impaired by Rh(null)-associated mutation
stated in qid: Q24300751
retrieved: 2018-03-27

source: Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles
stated in qid: Q24292672
retrieved: 2018-03-27

source: Molecular interactions with obscurin are involved in the localization of muscle-specific small ankyrin1 isoforms to subcompartments of the sarcoplasmic reticulum
stated in qid: Q24302073
retrieved: 2018-03-27

source: Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues
stated in qid: Q24291372
retrieved: 2018-03-27

source: Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor
stated in qid: Q24319665
retrieved: 2018-03-27

source: GOA
stated in qid: Q28018111
retrieved: 2018-03-27

source: Dissociation of spectrin-ankyrin complex as a basis for loss of Na-K-ATPase polarity after ischemia
stated in qid: Q24314760
retrieved: 2018-03-27

source: Immunocytochemical localization of fodrin and ankyrin in bovine chromaffin cells in vitro
stated in qid: Q24310155
retrieved: 2018-03-27

source: Ankyrin facilitates intracellular trafficking of alpha1-Na+-K+-ATPase in polarized cells
stated in qid: Q24310226
retrieved: 2018-03-27

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21097227
domain: protein
level: standard
html url: https://4ort.xyz/entity/ankyrin-1
markdown url: https://4ort.xyz/entity/ankyrin-1.md
facts url summary: https://4ort.xyz/entity/ankyrin-1/facts.json
facts url standard: https://4ort.xyz/entity/ankyrin-1/facts.json
facts url full: https://4ort.xyz/entity/ankyrin-1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-23T11:16:49.472883Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:12:18.107337+00:00Z