Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: Main-Spessart
additional property: PropertyValue
  property ID: P361
  value: nucleotide-diphospho-sugar transferases
additional property: PropertyValue
  property ID: P361
  value: N-acetylglucosaminyltransferase II
additional property: PropertyValue
  property ID: P637
  value: NP_002399
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P680
  value: alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
additional property: PropertyValue
  property ID: P680
  value: carbohydrate binding
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: Golgi membrane
additional property: PropertyValue
  property ID: P681
  value: Golgi stack
additional property: PropertyValue
  property ID: P682
  value: protein glycosylation
additional property: PropertyValue
  property ID: P682
  value: oligosaccharide biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: protein N-linked glycosylation
additional property: PropertyValue
  property ID: P702
  value: MGAT2
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000307423
additional property: PropertyValue
  property ID: P5806
  value: 77347007
additional property: PropertyValue
  property ID: P6694
  value: M0469827
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 14
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 14
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q10469
    source count: 1
    confidence: 0.2
    value label: Main-Spessart
  P361:
    value: Q24774250
    source count: 1
    confidence: 0.2
    value label: nucleotide-diphospho-sugar transferases
  P361:
    value: Q24780906
    source count: 1
    confidence: 0.2
    value label: N-acetylglucosaminyltransferase II
  P637:
    value: NP_002399
    source count: 1
    confidence: 0.2
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q21119444
    source count: 5
    confidence: 1.0
    value label: alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
  P680:
    value: Q14633866
    source count: 1
    confidence: 0.2
    value label: carbohydrate binding
  P680:
    value: Q14840132
    source count: 1
    confidence: 0.2
    value label: glycosyltransferase activity
  P680:
    value: Q21119444
    source count: 7
    confidence: 1.0
    value label: alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
  P681:
    value: Q14327652
    source count: 2
    confidence: 0.4
    value label: integral component of membrane
  P681:
    value: Q14598778
    source count: 2
    confidence: 0.4
    value label: Golgi membrane
  P681:
    value: Q14860351
    source count: 1
    confidence: 0.2
    value label: Golgi stack
  P681:
    value: Q83181
    source count: 2
    confidence: 0.4
    value label: Golgi apparatus
  P681:
    value: Q14349455
    source count: 3
    confidence: 0.6
    value label: membrane
  P682:
    value: Q14839643
    source count: 1
    confidence: 0.2
    value label: protein glycosylation
  P682:
    value: Q21109511
    source count: 1
    confidence: 0.2
    value label: oligosaccharide biosynthetic process
  P682:
    value: Q14861842
    source count: 2
    confidence: 0.4
    value label: protein N-linked glycosylation
  P682:
    value: Q14886346
    source count: 1
    confidence: 0.2
    value label: oligosaccharide metabolic process
  P682:
    value: Q14633895
    source count: 1
    confidence: 0.2
    value label: protein N-linked glycosylation via asparagine
  P702:
    value: Q18029079
    source count: 1
    confidence: 0.2
    value label: MGAT2
  P703:
    value: Q15978631
    source count: 1
    confidence: 0.2
    value label: Homo sapiens
  P705:
    value: ENSP00000307423
    source count: 1
    confidence: 0.2
  P5806:
    value: 77347007
    source count: 0
    confidence: 0.0
  P6694:
    value: M0469827
    source count: 0
    confidence: 0.0
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2017-09-26

source: The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein
stated in qid: Q24321959
retrieved: 2017-09-26

source: Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development
stated in qid: Q24675799
retrieved: 2019-04-08

source: Human N-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite
stated in qid: Q52318683
retrieved: 2019-04-08

source: The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein
stated in qid: Q24321959
retrieved: 2019-04-08

source: Golgi N-glycosyltransferases form both homo- and heterodimeric enzyme complexes in live cells
stated in qid: Q33885275
retrieved: 2019-04-08

source: Molecular cloning and expression of cDNA encoding the rat UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II
stated in qid: Q28116597
retrieved: 2017-09-26

source: Defining the membrane proteome of NK cells
stated in qid: Q24323157
retrieved: 2017-09-26

source: Defining the membrane proteome of NK cells
stated in qid: Q24323157
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21119445
domain: protein
level: standard
html url: https://4ort.xyz/entity/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-q21119445
markdown url: https://4ort.xyz/entity/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-q21119445.md
facts url summary: https://4ort.xyz/entity/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-q21119445/facts.json
facts url standard: https://4ort.xyz/entity/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-q21119445/facts.json
facts url full: https://4ort.xyz/entity/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-q21119445/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-12T14:33:18.237550Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:40:42.669745+00:00Z