Allograft inflammatory factor 1
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: O70200
additional property: PropertyValue
  property ID: P361
  value: EF-hand domain pair
additional property: PropertyValue
  property ID: P361
  value: membrane protein
additional property: PropertyValue
  property ID: P361
  value: EF-hand domain, protein family
additional property: PropertyValue
  property ID: P527
  value: EF-hand domain
additional property: PropertyValue
  property ID: P637
  value: NP_062340
additional property: PropertyValue
  property ID: P637
  value: XP_006523566
additional property: PropertyValue
  property ID: P637
  value: NP_001348430
additional property: PropertyValue
  property ID: P638
  value: 1WY9
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P680
  value: calcium ion binding
additional property: PropertyValue
  property ID: P680
  value: actin binding
additional property: PropertyValue
  property ID: P681
  value: phagocytic cup
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: ruffle
additional property: PropertyValue
  property ID: P682
  value: Rac protein signal transduction
additional property: PropertyValue
  property ID: P682
  value: cellular response to hormone stimulus
additional property: PropertyValue
  property ID: P682
  value: cellular response to hydroperoxide
additional property: PropertyValue
  property ID: P702
  value: Aif1
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000025257
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000133709
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000134214
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 15
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 15
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: O70200
    source count: 1
    confidence: 0.2
  P361:
    value: Q24742069
    source count: 1
    confidence: 0.2
    value label: EF-hand domain pair
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83134678
    source count: 1
    confidence: 0.2
    value label: EF-hand domain, protein family
  P527:
    value: Q24723907
    source count: 1
    confidence: 0.2
    value label: EF-hand domain
  P637:
    value: NP_062340
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006523566
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001348430
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001348431
    source count: 1
    confidence: 0.2
  P638:
    value: 1WY9
    source count: 1
    confidence: 0.2
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding
  P680:
    value: Q14633862
    source count: 2
    confidence: 0.4
    value label: calcium ion binding
  P680:
    value: Q14863962
    source count: 1
    confidence: 0.2
    value label: actin binding
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q14860806
    source count: 3
    confidence: 0.6
    value label: actin filament binding
  P681:
    value: Q15325702
    source count: 3
    confidence: 0.6
    value label: phagocytic cup
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q14860430
    source count: 1
    confidence: 0.2
    value label: ruffle
  P681:
    value: Q29548
    source count: 1
    confidence: 0.2
    value label: plasma membrane
  P681:
    value: Q154626
    source count: 1
    confidence: 0.2
    value label: cytoskeleton
  P682:
    value: Q15316101
    source count: 1
    confidence: 0.2
    value label: Rac protein signal transduction
  P682:
    value: Q14864711
    source count: 1
    confidence: 0.2
    value label: cellular response to hormone stimulus

value: Q14864570
source count: 1
confidence: 0.2
value label: cellular response to hydroperoxide

value: Q14860535
source count: 1
confidence: 0.2
value label: response to cytokine

value: Q14885640
source count: 2
confidence: 0.4
value label: cellular response to interferon-gamma

value: Q18247660
source count: 1
confidence: 0.2
value label: Aif1

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000025257
source count: 1
confidence: 0.2

value: ENSMUSP00000133709
source count: 1
confidence: 0.2

value: ENSMUSP00000134214
source count: 1
confidence: 0.2

value: ENSMUSP00000134107
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-04-24

source: X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding
stated in qid: Q24305295
retrieved: 2018-04-24

source: Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity
stated in qid: Q28241890
retrieved: 2019-02-14

source: X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding
stated in qid: Q24305295
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2018-09-10

source: Iba1 is an actin-cross-linking protein in macrophages/microglia
stated in qid: Q28212285
retrieved: 2019-02-14

source: Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia
stated in qid: Q28508347
retrieved: 2019-02-14

source: Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia
stated in qid: Q28508347
retrieved: 2018-04-24

source: Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity
stated in qid: Q28241890
retrieved: 2018-04-24

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21494784
domain: protein
level: standard
html url: https://4ort.xyz/entity/allograft-inflammatory-factor-1
markdown url: https://4ort.xyz/entity/allograft-inflammatory-factor-1.md
facts url summary: https://4ort.xyz/entity/allograft-inflammatory-factor-1/facts.json
facts url standard: https://4ort.xyz/entity/allograft-inflammatory-factor-1/facts.json
facts url full: https://4ort.xyz/entity/allograft-inflammatory-factor-1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T12:46:09.664488Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:50.900290+00:00Z