# Alkaline ceramidase 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21154283](https://www.wikidata.org/wiki/Q21154283)  
**Source**: https://4ort.xyz/entity/alkaline-ceramidase-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9NUN7)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NUN7)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NUN7&geneProductId=UniProtKB:Q9NUN7)
6. [Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NUN7&geneProductId=UniProtKB:Q9NUN7)
7. [Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NUN7&geneProductId=UniProtKB:Q9NUN7)
8. [Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NUN7)
9. [Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NUN7)
10. [Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NUN7)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NUN7)
12. [Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NUN7)
13. [Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NUN7)
14. [Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NUN7&geneProductId=UniProtKB:Q9NUN7)
15. [Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NUN7&geneProductId=UniProtKB:Q9NUN7)
16. Ensembl Release 99