# Alchemical Metadynamics: Adding Alchemical Variables to Metadynamics to Enhance Sampling in Free Energy Calculations

> Research article (Journal of Chemical Theory and Computation, 2023) · cited 26× · AI/ML

**Wikidata**: [openalex:W4322603972](https://www.wikidata.org/wiki/openalex:W4322603972)  
**Source**: https://4ort.xyz/entity/alchemical-metadynamics-adding-alchemical-variables-to-metadynamics-to-enhance-sampling-in-free-energy-calculations