# AKT serine/threonine kinase 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116540](https://www.wikidata.org/wiki/Q21116540)  
**Source**: https://4ort.xyz/entity/akt-serine-threonine-kinase-3-q21116540


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1079175)
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2219422)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2325741)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL494089)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2177390)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL3137336)
8. Q20641742
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
10. [A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y243&geneProductId=UniProtKB:Q9Y243)
12. [Kinetic mechanism of AKT/PKB enzyme family](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y243&geneProductId=UniProtKB:Q9Y243)
13. [The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
14. [The E3 ligase TRAF6 regulates Akt ubiquitination and activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
15. [Caspase-3-mediated cleavage of Akt: involvement of non-consensus sites and influence of phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
16. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
17. [A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
18. [Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
19. [Kinetic mechanism of AKT/PKB enzyme family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
21. [VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
22. [MicroRNA-22 Induces Endothelial Progenitor Cell Senescence by Targeting AKT3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
23. [MiR-15b-5p Regulates Collateral Artery Formation by Targeting AKT3 (Protein Kinase B-3).](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y243)
24. Ensembl Release 99