# AKT serine/threonine kinase 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116502](https://www.wikidata.org/wiki/Q21116502)  
**Source**: https://4ort.xyz/entity/akt-serine-threonine-kinase-2


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
4. [Akt1 and Akt2: differentiating the aktion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751)
6. [AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751)
7. [Kinetic mechanism of AKT/PKB enzyme family](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751)
8. [The protooncogene TCL1 is an Akt kinase coactivator](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751)
9. [The protooncogene TCL1 is an Akt kinase coactivator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
10. [A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
11. [Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
12. [Interactions between GIPC–APPL and GIPC–TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
13. [The E3 ligase TRAF6 regulates Akt ubiquitination and activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
14. [Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
15. [The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
16. [Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
17. [Systematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
18. [Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
19. [Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
20. [Vimentin is a novel AKT1 target mediating motility and invasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
21. [APPL1, APPL2, Akt2 and FOXO1a interact with FSHR in a potential signaling complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
22. [Kinetic mechanism of AKT/PKB enzyme family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
23. [Akt1 and Akt2: differentiating the aktion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
24. [AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
26. [siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
27. [Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
28. [MicroRNA-29s could target AKT2 to inhibit gastric cancer cells invasion ability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751)
29. [siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751)
30. Ensembl Release 99