# AKT serine/threonine kinase 2

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558079](https://www.wikidata.org/wiki/Q28558079)  
**Source**: https://4ort.xyz/entity/akt-serine-threonine-kinase-2-q28558079


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
4. [The phosphatidylinositol 3-kinase/Akt signaling pathway modulates the endocrine differentiation of trophoblast cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
5. [Altered subcellular distribution of IRS-1 and IRS-3 is associated with defective Akt activation and GLUT4 translocation in insulin-resistant old rat adipocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
6. [Akt kinases and 2-deoxyglucose uptake in rat skeletal muscles in vivo: study with insulin and exercise](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
7. [Akt-2 binds to Glut4-containing vesicles and phosphorylates their component proteins in response to insulin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
9. [Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
10. [The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
11. [Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
12. [Mitochondrial genome modulates myocardial Akt/GLUT/HK salvage pathway in spontaneously hypertensive rats adapted to chronic hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
13. [Insulin Increases the Association of Akt-2 with Glut4-containing Vesicles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
14. [Control of muscle mitochondria by insulin entails activation of Akt2-mtNOS pathway: implications for the metabolic syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
15. [Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
16. [Retinal insulin receptor signaling in hyperosmotic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
17. [The role of Akt/protein kinase B subtypes in retinal ischemic preconditioning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
18. [Antisense and dominant-negative AKT2 cDNA inhibits glioma cell invasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
19. [Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
20. [Contraction regulation of Akt in rat skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
21. [Reduction of Akt2 inhibits migration and invasion of glioma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
22. [Maternal protein restriction leads to early life alterations in the expression of key molecules involved in the aging process in rat offspring](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
23. [Prolactin-modulated gene expression profiles in pancreatic islets from adult female rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
24. [Enhanced protection against cytokine- and fatty acid-induced apoptosis in pancreatic beta cells by combined treatment with glucagon-like peptide-1 receptor agonists and insulin analogues](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
25. [Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
26. [Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47197)
27. ensembl Release 104