# advanced glycosylation end-product specific receptor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q22683568](https://www.wikidata.org/wiki/Q22683568)  
**Source**: https://4ort.xyz/entity/advanced-glycosylation-end-product-specific-receptor


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q15109)
3. Q20641742
4. [S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
6. [Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
7. [In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
8. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
9. [TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
10. [Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
11. [An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
12. [S100P promotes pancreatic cancer growth, survival, and invasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
13. [Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
14. [Structural and functional insights into RAGE activation by multimeric S100B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
15. [S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
16. [Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
17. [Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
18. [Advanced glycation end products increase endothelial permeability through the RAGE/Rho signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
19. [Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
20. [Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
21. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q15109)
22. [The Cellular Phase of Alzheimer's Disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15109&geneProductId=UniProtKB:Q15109)
23. [RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15109&geneProductId=UniProtKB:Q15109)
24. [Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15109&geneProductId=UniProtKB:Q15109)
25. [A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15109&geneProductId=UniProtKB:Q15109)
26. [Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
27. [RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
28. [RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
29. [The Cellular Phase of Alzheimer's Disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
30. [Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
31. [A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
32. [TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
33. [Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q15109)
34. [Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
35. [Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
36. [HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
37. [Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced glycation end products](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
38. [Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
39. [RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
40. [Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q15109)
41. [Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
42. [Regulation of RAGE splicing by hnRNP A1 and Tra2β‐1 and its potential role in AD pathogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
43. [beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
44. [RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
45. [Microglial receptor for advanced glycation end product-dependent signal pathway drives beta-amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
46. [Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: the role of RAGE](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15109)
47. Ensembl Release 99
48. UMLS 2023
49. Transporter Classification database